{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T06:13:42Z","timestamp":1696486422773},"reference-count":41,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T00:00:00Z","timestamp":1470787200000},"content-version":"vor","delay-in-days":9,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Prim\u00e4r kutane CD30<jats:sup>+<\/jats:sup> lymphoproliferative Erkrankungen z\u00e4hlen zu der zweit h\u00e4ufigsten Gruppe der kutanen T\u2010Zell\u2010Lymphome (CTCL) und umfassen die Krankheitsbilder der lymphomatoiden Papulose (LyP) und des prim\u00e4r kutanen anaplastischen gro\u00dfzelligen Lymphoms (cALCL). Beide Erkrankungen haben klinische, histopathologische und molekulare Gemeinsamkeiten und repr\u00e4sentieren ein Spektrum von kutanen CD30<jats:sup>+<\/jats:sup> lymphoproliferativen Erkrankungen. Man kann LyP vom cALCL anhand des Zusammenspiels von klinischen und histopathologischen Befunden unterscheiden. In manchen Patienten k\u00f6nnen LyP und MF gemeinsam auftreten, oder k\u00f6nnen w\u00e4hrend des Krankheitsverlaufes entstehen. Mycosis fungoides (MF), ist die h\u00e4ufigste Form von CTCL und z\u00e4hlt nicht zur Gruppe der prim\u00e4r kutanen CD30<jats:sup>+<\/jats:sup> lymphoproliferativen Erkrankungen. Manche LyP\u2010Patienten k\u00f6nnen jedoch von beiden Krankheitsbildern gemeinsam betroffen sein. Es ist aber auch m\u00f6glich, dass ein MF\u2010Patient LyP\u2010artige L\u00e4sionen entwickelt, die eher eine Manifestation der MF darstellen als zwei unterschiedliche Erkrankungen. Besondere Vorsicht ist jedoch im Zusammenhang mit CD30<jats:sup>+<\/jats:sup> transformierten MF\u2010L\u00e4sionen geboten, da die Gefahr besteht, dass diese f\u00e4lschlicherweise als LyP oder cALCL diagnostiziert werden, was m\u00f6glicherweise zu einer inad\u00e4quaten Behandlung f\u00fchrt.<\/jats:p>","DOI":"10.1111\/ddg.13117_g","type":"journal-article","created":{"date-parts":[[2016,8,10]],"date-time":"2016-08-10T13:35:44Z","timestamp":1470836144000},"page":"767-784","source":"Crossref","is-referenced-by-count":0,"title":["Prim\u00e4r kutane CD30<sup>+<\/sup> lymphoproliferative Erkrankungen"],"prefix":"10.1111","volume":"14","author":[{"given":"Iris","family":"Wieser","sequence":"first","affiliation":[{"name":"Dermatologisches Institut der Universit\u00e4t Texas, MD Anderson Cancer Center  Houston Texas U.S.A"},{"name":"Dermatologisches Institut der Paracelsus Medizinischen Privatuniversit\u00e4t  Salzburg \u00d6sterreich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael T.","family":"Tetzlaff","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie und Institut f\u00fcr Translationale und Molekulare Pathologie Universit\u00e4t Texas, MD Anderson Krebszentrum  Houston Texas U.S.A"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos A. 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