{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,11,19]],"date-time":"2024-11-19T17:16:24Z","timestamp":1732036584364},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T00:00:00Z","timestamp":1489536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Rising incidence rates of HIV and STIs (sexually transmitted infections) among MSM (men who have sex with men) in Germany since 2001 call for new approaches in medical prevention. The present study addresses appropriate parameters to identify those HIV\u2010positive MSM who are at high risk for transmitting HIV and STIs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>Over a two\u2010year period, 223 HIV\u2010positive MSM attending the HIV outpatient clinic at the University Medical Center Essen (Germany) were systematically surveyed with respect to their sexual behavior, substance abuse, and psychological well\u2010being in the preceding year. Data analyzed included laboratory and clinical data from the time of the initial HIV diagnosis until January 2014.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In HIV\u2010positive MSM, a history of substance abuse, promiscuity, younger age, and known STIs was associated with a greater incidence of unprotected sexual intercourse and STIs. Apart from a detectable viral load, additional HIV\u2010specific parameters associated with an increased HIV transmission risk included untreated HIV infection, adherence problems, changes in antiretroviral treatment over the preceding twelve months, known multiresistant HIV infection, and a higher CD 4 nadir. Despite routine quarterly monitoring of viral loads \u2013 the result thereof was communicated to patients \u2013 only 60\u00a0% of individuals assessed their HIV transmission risk correctly.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In HIV\u2010positive MSM, patient history and routine laboratory tests allow for the establishment of patient profiles that suggest sexual behavior associated with a high risk of HIV and STI transmission, thus offering new approaches for medical prevention.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ddg.13217","type":"journal-article","created":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T10:23:13Z","timestamp":1489573393000},"page":"421-428","source":"Crossref","is-referenced-by-count":10,"title":["Sexual risk behavior, sexually transmitted infections, and HIV transmission risks in HIV\u2010positive men who have sex with men (MSM) \u2013 approaches for medical prevention"],"prefix":"10.1111","volume":"15","author":[{"given":"Stefan","family":"Esser","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, Outpatient Clinic for HIV and STIs University Medical Center Duisburg\u2010Essen  Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Krotzek","sequence":"additional","affiliation":[{"name":"Children's Hospital Datteln University Witten\/Herdecke  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henrike","family":"Dirks","sequence":"additional","affiliation":[{"name":"Addiction Research Group at the Department of Psychiatry and Psychotherapy University Medical Center Duisburg\u2010Essen, LVR Hospital Essen  Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Scherbaum","sequence":"additional","affiliation":[{"name":"Addiction Research Group at the Department of Psychiatry and Psychotherapy University Medical Center Duisburg\u2010Essen, LVR Hospital Essen  Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Schadendorf","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Outpatient Clinic for HIV and STIs University Medical Center Duisburg\u2010Essen  Essen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,15]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.5148"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105243"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60936-1"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1506816"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055312"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3282fd167c"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4414\/saez.2008.13252"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1086\/656809"},{"key":"e_1_2_7_10_1","unstructured":"Deutsche AIDS\u2010Hilfe e.V.: HIV\u2010Therapie und Pr\u00e4vention. 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