{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:09:09Z","timestamp":1790287749453,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T00:00:00Z","timestamp":1491350400000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The nail apparatus is an integral part of the functional unit of the digital tip. Although overall uncommon, all cells and tissues occurring in this area can give rise to neoplastic lesions. Given the special anatomical location, such tumors frequently show morphological and symptom\u2010related differences compared to similar lesions located elsewhere on the skin. Though particularly threatening, there is often a substantial delay in the diagnosis of Bowen's disease, ungual squamous cell carcinoma, and melanoma. Nevertheless, local excision with sufficient surgical margins is usually sufficient and superior to amputation of the distal phalanx. In recent years, a number of nail\u2010specific tumors have been described. Tumors such as onychomatricoma, onychocytic matricoma, onychocytic carcinoma, and onychopapilloma originate from the nail matrix. Onycholemmal cysts, onycholemmal horn, and the proliferating onycholemmal tumor are characteristic nail bed tumors. Onycholemmal carcinoma is a slowly growing low\u2010grade malignancy.<\/jats:p><jats:p>Using modern diagnostic methods, careful examination \u2013 including biopsy and histopathology \u2013 of nail changes not responding to conservative treatment will help identify nail\u2010specific neoplasms and prevent the progression of malignant nail tumors.<\/jats:p>","DOI":"10.1111\/ddg.13223","type":"journal-article","created":{"date-parts":[[2017,4,5]],"date-time":"2017-04-05T18:53:04Z","timestamp":1491418384000},"page":"367-386","source":"Crossref","is-referenced-by-count":32,"title":["Important malignant and new nail tumors"],"prefix":"10.1111","volume":"15","author":[{"given":"Eckart","family":"Haneke","sequence":"first","affiliation":[{"name":"Department of Dermatology, Inselspital University of Bern  Bern Switzerland"},{"name":"Dermatology Practice Dermaticum  Freiburg Germany"},{"name":"Centro de Dermatolog\u00eda Instituto CUF, Senhora da Hora, Matosinhos  Grande Porto Portugal"},{"name":"Department of Dermatology University Hospital  Ghent Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,5]]},"reference":[{"key":"e_1_2_20_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-013-2705-z"},{"key":"e_1_2_20_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13654"},{"key":"e_1_2_20_4_1","unstructured":"Kurzleitlinie \u2013 Plattenepithelkarzinom der Haut. Update 2012. S2k\u2010Leitlinie 032\/022: Plattenepithelkarzinom der Haut aktueller Stand: 12\/2013 Available onhttp:\/\/www.awmf.org\/uploads\/tx_szleitlinien\/032\u2010022l_S2k_Plattenepithelkarzinom_2013\u2010verlaengert.pdf[Last accessed December 24 2016]."},{"key":"e_1_2_20_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1529-8019.2012.01515.x"},{"key":"e_1_2_20_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2010.43"},{"key":"e_1_2_20_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3182545ccd"},{"key":"e_1_2_20_8_1","first-page":"389","article-title":"Subunguales Melanom mit streifiger Nagelpigmentierung","volume":"29","author":"Haneke E","year":"1978","journal-title":"Hautarzt"},{"key":"e_1_2_20_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-4725.2003.29087.x"},{"key":"e_1_2_20_10_1","unstructured":"Leitlinienprogramm Onkologie (Deutsche Krebsgesellschaft Deutsche Krebshilfe AWMF): Diagnostik Therapie und Nachsorge des Melanoms Langversion 2.0 2016 AWMF\u2010Registernummer: 032\/024OL. Available onhttp:\/\/leitlinienprogramm\u2010onkologie.de\/Melanom.65.0.html[Last accessed December 24 2016]: 43."},{"key":"e_1_2_20_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.41"},{"key":"e_1_2_20_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31824a0b83"},{"key":"e_1_2_20_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000249772"},{"key":"e_1_2_20_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1992.tb15125.x"},{"key":"e_1_2_20_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e31822c3d8b"},{"key":"e_1_2_20_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0b013e3182827fec"},{"key":"e_1_2_20_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.08.053"},{"key":"e_1_2_20_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.2009.01276.x"},{"key":"e_1_2_20_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.08.004"},{"key":"e_1_2_20_20_1","unstructured":"HanekeE.Common and uncommon nail tumours. 20thDermatopathology Meeting Vars France 29.1.\u20134.2. 2012."},{"key":"e_1_2_20_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1994.tb00256.x"},{"key":"e_1_2_20_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2012.07.015"},{"key":"e_1_2_20_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(00)90137-3"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fddg.13223","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.13223","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T17:24:56Z","timestamp":1696353896000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.13223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["10.1111\/ddg.13223"],"URL":"https:\/\/doi.org\/10.1111\/ddg.13223","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4]]}}}