{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:11:14Z","timestamp":1787314274590,"version":"build-2736575974"},"reference-count":49,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Associated with a host of different diseases, pruritus is a cardinal symptom that poses an interdisciplinary diagnostic and therapeutic challenge. Over time, that symptom may progress independently of the initial cause, thus losing its function as a warning sign and turning into a clinically relevant disease of its own. In Germany, approximately 13.5\u00a0% of the general population are affected by chronic pruritus, with an incidence of 7\u00a0%. All forms of chronic pruritus require targeted treatment consisting of (a) diagnosis and management of the underlying disease, (b) dermatological treatment of primary or secondary (for example, dry skin, scratch lesions) symptoms, (c) symptomatic antipruritic treatment, and (d) psychological\/psychotherapeutic treatment in case of an underlying or associated psychological or psychosomatic condition. Medical care of patients with chronic pruritus should therefore include an interdisciplinary approach, in particular with respect to diagnosis and therapy of the underlying disease as well as in terms of the management of treatment and adverse events. The objective of the present interdisciplinary guidelines is to define and standardize diagnostic and therapeutic procedures in patients with chronic pruritus. This is a short version of the current S2 guidelines on chronic pruritus. The long version may be found at\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.awmf.org\">www.awmf.org<\/jats:ext-link>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/ddg.13304","type":"journal-article","created":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T13:15:28Z","timestamp":1501593328000},"page":"860-872","source":"Crossref","is-referenced-by-count":17,"title":["S2k Guidelines for the diagnosis and treatment of chronic pruritus \u2013 update \u2013 short version"],"prefix":"10.1111","volume":"15","author":[{"given":"Sonja","family":"St\u00e4nder","sequence":"first","affiliation":[{"name":"Center for Chronic Pruritus (KCP) and Department of Dermatology University Medical Center  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Zeidler","sequence":"additional","affiliation":[{"name":"Center for Chronic Pruritus (KCP) and Department of Dermatology University Medical Center  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Augustin","sequence":"additional","affiliation":[{"name":"Institute for Health Care Research in Dermatology and Nursing (IVDP), Competence Center for Nursing Research in Dermatology (CVderm) University Medical Center Hamburg\u2010Eppendorf  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudrun","family":"Bayer","sequence":"additional","affiliation":[{"name":"Institute of General Medicine Charit\u00e9 \u2013 University Medical Center  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas E.","family":"Kremer","sequence":"additional","affiliation":[{"name":"Department of Medicine I, Gastroenterology, Pulmonology, and Endocrinology University of Erlangen\u2010Nuremberg  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz J.","family":"Legat","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology Graz Medical University  Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Maisel","sequence":"additional","affiliation":[{"name":"Center for General Medicine, Medical Faculty University of M\u00fcnster  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Mettang","sequence":"additional","affiliation":[{"name":"Department of Nephrology DKD Helios Klinik  Wiesbaden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Metz","sequence":"additional","affiliation":[{"name":"Allergy Center Charit\u00e9, Department of Dermatology, Venereology, and Allergology Charit\u00e9 \u2013 University Medical Center  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Nast","sequence":"additional","affiliation":[{"name":"Division of Evidence\u2010Based Medicine (dEBM), Department of Dermatology, Venereology, and Allergology Charit\u00e9 \u2013 University Medical Center  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Niemeier","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology, and Allergology University Medical Center Giessen and Marburg (Giessen site) and Practice for Dermatology, Psychotherapy, and Psychoanalysis  Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Raap","sequence":"additional","affiliation":[{"name":"Department of Dermatology Allergology Faculty of Medicine and Health Science, University of Oldenburg, Klinikum Oldenburg A\u00f6R, Oldenburg  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudrun","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Psychosomatic Medicine and Psychotherapy University Medical 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