{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T08:44:52Z","timestamp":1696063492883},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,1,8]],"date-time":"2018-01-08T00:00:00Z","timestamp":1515369600000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Die erosive pustul\u00f6se Dermatose der Kopfhaut (EPDK) ist eine entz\u00fcndliche Erkrankung unbekannter \u00c4tiologie. Wir besprechen die EPDK und pr\u00e4sentieren unsere eigene klinische und histopathologische Erfahrung von elf Patienten. Die EPDK neigt dazu, spontan die kahle Kopfhaut \u00e4lterer Patienten zu befallen. Anamnestisch wird h\u00e4ufig \u2013 so auch bei vier unserer Patienten \u2013 eine vorausgegangene Operation an selbiger Stelle angegeben. Koronare Herzerkrankung, cerebraler Insult, arterieller Hypertonus, Diabetes mellitus und ernste Krebserkrankungen wurden ebenfalls h\u00e4ufig als Komorbidit\u00e4t diagnostiziert. Die meisten Patienten zeigen trotz antiinflammatorischer Lokaltherapie einen schwankenden klinischen Verlauf, bei einigen heilt die L\u00e4sion unter Narbenbildung ab. Histopathologisch findet sich eine Kruste oder Erosion mit Granulationsgewebe\u2010\u00e4hnlichen Ver\u00e4nderungen im Korium mit sp\u00e4terer Entstehung einer Narbe. Neben einer lokalen und aktinischen Sch\u00e4digung k\u00f6nnten eine eingeschr\u00e4nkte Immunit\u00e4t und Mikrozirkulation pr\u00e4disponierende Faktoren der Erkrankung sein. Analog zum Pyoderma gangraenosum muss die EPDK bei nichtheilenden Wunden \u00e4lterer Patienten bedacht werden, nachdem die Differenzialdiagnosen, die diese Erkrankung simulieren, ausgeschlossen wurden. Da vorausgegangene oder benachbarte Basalzell\u2010 und insbesondere Plattenepithelkarzinome h\u00e4ufig sind und infiltrative Varianten jenseits des klinisch sichtbaren Krankheitsprozesses vorkommen, kann im Zweifelsfall eine sogenannte histologische Kartierung der umgebenden Haut ratsam sein.<\/jats:p>","DOI":"10.1111\/ddg.13387_g","type":"journal-article","created":{"date-parts":[[2018,1,13]],"date-time":"2018-01-13T03:50:33Z","timestamp":1515815433000},"page":"15-20","source":"Crossref","is-referenced-by-count":1,"title":["Erosive pustul\u00f6se Dermatose der Kopfhaut: Neubewertung einer zu wenig beachteten Entit\u00e4t"],"prefix":"10.1111","volume":"16","author":[{"given":"Michael","family":"Wilk","sequence":"first","affiliation":[{"name":"Dermatohistologisches Labor und Hautarztpraxis  N\u00fcrnberg"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bettina G.","family":"Zelger","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Pathologie Medizinische Universit\u00e4t Innsbruck"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Undine","family":"Hauser","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Dermatologie Venerologie und Allergologie Medizinische Universit\u00e4t Innsbruck"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhard","family":"H\u00f6pfl","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Dermatologie Venerologie und Allergologie Medizinische Universit\u00e4t Innsbruck"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Zelger","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik f\u00fcr Dermatologie Venerologie und Allergologie Medizinische Universit\u00e4t Innsbruck"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,1,8]]},"reference":[{"key":"e_1_2_3_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1977.tb14339.x"},{"key":"e_1_2_3_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1979.tb05581.x"},{"key":"e_1_2_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.04.026"},{"key":"e_1_2_3_5_1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1365-2230.1988.tb00639.x","article-title":"Evidence for a role of local trauma in the pathogenesis of erosive pustular dermatosis of the scalp","volume":"13","author":"Gratton CE","year":"1988","journal-title":"Clin Exp Dermatol"},{"key":"e_1_2_3_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.10.011"},{"key":"e_1_2_3_7_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2015.2528"},{"key":"e_1_2_3_8_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1602"},{"key":"e_1_2_3_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2009.278"},{"key":"e_1_2_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.09.006"},{"key":"e_1_2_3_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000341528"},{"key":"e_1_2_3_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13350"},{"key":"e_1_2_3_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2011.05.008"},{"key":"e_1_2_3_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.1999.00546.x"},{"key":"e_1_2_3_15_1","first-page":"177","article-title":"Erosive pustular dermatosis (chronic atrophic dermatosis of the scalp and extremities)","volume":"6","author":"Semkova K","year":"2013","journal-title":"Clin Cosmet Investig Dermatol"},{"key":"e_1_2_3_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/DAD.0000000000000100"},{"key":"e_1_2_3_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05094.x"},{"key":"e_1_2_3_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2011.01.003"},{"key":"e_1_2_3_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.03312.x"},{"key":"e_1_2_3_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4362.1995.tb03605.x"},{"key":"e_1_2_3_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12812"},{"key":"e_1_2_3_22_1","doi-asserted-by":"publisher","DOI":"10.1159\/000210430"},{"key":"e_1_2_3_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000246066"},{"key":"e_1_2_3_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2009.00478.x"},{"key":"e_1_2_3_25_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2015.6300"},{"key":"e_1_2_3_26_1","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1007\/978-3-642-24163-5_41","volume-title":"Braun\u2010Falco\u2019s Dermatologie, Venerologie und Allergologie. 6. 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