{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T08:14:58Z","timestamp":1792224898833,"version":"4.4.0"},"reference-count":55,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T00:00:00Z","timestamp":1543276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Scabies has been diagnosed surprisingly frequently in Germany in recent years, and the use of acaricides has risen markedly. Present figures indicate an increase in the prevalence\/incidence of scabies, but do not prove or quantify it for the following reasons: (a) scabies is not a notifiable disease in Germany; (b) the diagnosis is not always confirmed <jats:italic>lege artis<\/jats:italic> by means of light microscopy or dermatoscopy (which may lead to a comparatively high proportion of false\u2010positive diagnoses due to the low overall prevalence of scabies); (c) repeated treatments of the same patient and treatment of contact persons are included in the total number of prescriptions. Therefore, there are no valid data on disease occurrence, either in the current situation or from previous periods.<\/jats:p><jats:p>Observations of ineffective treatment with permethrin have led to speculations that Sarcoptes mites are developing resistance to this drug. However, there is little evidence for this assumption.<\/jats:p><jats:p>We discuss risk groups (children, elderly people in need of care, migrant health personnel in nursing institutions, refugees, sexually active young adults) and evaluate their possible contribution, albeit in the absence of evidence. None of the groups would be solely responsible for an increased frequency.<\/jats:p><jats:p>We have compiled recommendations on how the management of scabies could be improved, and present a way of differentiating permethrin resistance from application errors and\/or lack of compliance. The goal is to solve the epidemiological and parasitological questions mentioned above.<\/jats:p>","DOI":"10.1111\/ddg.13706","type":"journal-article","created":{"date-parts":[[2018,11,27]],"date-time":"2018-11-27T18:10:32Z","timestamp":1543342232000},"page":"15-23","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":62,"title":["Increase of scabies in Germany and development of resistant mites? Evidence and consequences"],"prefix":"10.1111","volume":"17","author":[{"given":"Cord","family":"Sunderk\u00f6tter","sequence":"first","affiliation":[{"name":"University Hospital of Halle, Department of Dermatology and Venereology  Halle (Saale) Germany"},{"name":"Department of Translational Dermatoinfectiology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Aebischer","sequence":"additional","affiliation":[{"name":"Robert Koch-Institute  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Neufeld","sequence":"additional","affiliation":[{"name":"Department of Translational Dermatoinfectiology University of Muenster  Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"L\u00f6ser","sequence":"additional","affiliation":[{"name":"Skin Cancer Center Department of Dermatology Ludwigshafen Medical Center  Ludwigshafen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Kreuter","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venerology and Allergology HELIOS St Elisabeth Hospital Oberhausen University Witten\/Herdecke Oberhausen Witten  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Bialek","sequence":"additional","affiliation":[{"name":"LADR GmbH MVZ Dr. Kramer and Kollegen  Geesthacht Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henning","family":"Hamm","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology University Hospital W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermann","family":"Feldmeier","sequence":"additional","affiliation":[{"name":"Institute of Microbiology and Hygiene Charit\u00e9 \u2013 University Medicine  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,27]]},"reference":[{"key":"e_1_2_10_2_1","first-page":"700","article-title":"Skabies: Erfahrungen aus der Praxis","volume":"115","author":"K\u00e4mmerer E.","year":"2018","journal-title":"Dtsch Arztebl International"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s15011-017-1175-5"},{"key":"e_1_2_10_4_1","unstructured":"http:\/\/www.gbe-bund.de[Last accessed August 22 2018]."},{"key":"e_1_2_10_5_1","unstructured":"https:\/\/www.barmer.de\/presse\/presseinformationen\/pressemitteilungen\/kraetze-vormarsch-147122[Last accessed August 22 2018]."},{"key":"e_1_2_10_6_1","unstructured":"https:\/\/www.gesetze-im-internet.de\/ifsg\/[Last accessed August 22 2018]."},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68772-2"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30483-8"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10264.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/014107680509800313"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.331.7517.619"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-012-1752-1"},{"key":"e_1_2_10_13_1","first-page":"25","volume-title":"Recent advances in paediatrics 24","author":"Feldmeier H","year":"2007"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-2880"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.13130"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)93239-6"},{"key":"e_1_2_10_17_1","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-658-17622-8","volume-title":"Infektionsepidemiologisches Jahrbuch meldepflichtiger Krankheiten f\u00fcr 2016","author":"Institut RK.","year":"2017"},{"key":"e_1_2_10_18_1","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1001\/archderm.1978.01640170047009","article-title":"The epidemiology of scabies in Denmark, 1900 to 1975","volume":"114","author":"Christophersen J","year":"1978","journal-title":"Arch Dermatol"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00103-016-2332-9"},{"key":"e_1_2_10_20_1","article-title":"Gesundheit und gesundheitliche Versorgung von Asylsuchenden und Fl\u00fcchtlingen in Deutschland","author":"Frank L","year":"2017","journal-title":"Robert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0179537"},{"key":"e_1_2_10_22_1","volume-title":"2016 Annual Report on intra-EU Labour Mobility","author":"Fries-Tersch E","year":"2017"},{"key":"e_1_2_10_23_1","unstructured":"https:\/\/statistik.arbeitsagentur.de\/Navigation\/Statistik\/Statistik-nach-Themen\/Migration\/Personen-nach-Staatsangehoerigkeiten\/Personen-nach-Staatsangehoerigkeiten-Nav.html[Last accessed August 22 2018]."},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhin.2006.08.012"},{"key":"e_1_2_10_25_1","unstructured":"https:\/\/www.destatis.de\/DE\/ZahlenFakten\/GesellschaftStaat\/Bevoelkerung\/MigrationIntegration\/MigrationIntegration.html[Last accessed August 22 2018]."},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2010.19.1.45910"},{"key":"e_1_2_10_27_1","first-page":"CD012994","article-title":"Ivermectin and permethrin for treating scabies","volume":"4","author":"Rosumeck S","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_10_28_1","first-page":"757","article-title":"The Treatment of Scabies","volume":"113","author":"Dressler C","year":"2016","journal-title":"Dtsch Arztebl Int"},{"key":"e_1_2_10_29_1","first-page":"9","article-title":"[Therapeutic failure in scabies: An observational study]","volume":"143","author":"Sainte Marie B","year":"2016","journal-title":"Ann Dermatol Venereol"},{"key":"e_1_2_10_30_1","first-page":"397","article-title":"A review of patient adherence to topical therapies for treatment of atopic dermatitis","volume":"96","author":"Snyder A","year":"2015","journal-title":"Cutis"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1080\/09546634.2016.1181256"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.4211.405"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/pde.12473"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-3-43"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2915.2008.00716.x"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000354"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(00)90454-1"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12334"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005920"},{"key":"e_1_2_10_40_1","article-title":"A persistent problem with scabies in and outside a nursing home in Amsterdam: indications for resistance to lindane and ivermectin","volume":"13","author":"den Hoek JA","year":"2008","journal-title":"Euro Surveill"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1086\/421776"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.2217\/17460913.3.1.57"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0166-6851(97)00215-6"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5541.669"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2004.08.033"},{"key":"e_1_2_10_46_1","unstructured":"https:\/\/www.infektionsschutz.de\/erregersteckbriefe\/kraetze-skabies\/[Last accessed August 30 2018]."},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199507063330105"},{"key":"e_1_2_10_48_1","unstructured":"https:\/\/www.cdc.gov\/std\/tg2015\/ectoparasitic.htm[Last accessed August 22 2018]."},{"key":"e_1_2_10_49_1","first-page":"584","article-title":"Crusted scabies and multiple dosages of ivermectin","volume":"12","author":"Ortega-Loayza AG","year":"2013","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.3109\/09546634.2016.1151855"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1990.01670310130025"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-1470.2012.01745.x"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1001\/archdermatol.2011.51"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.45.1707"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.07.025"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.13438_g"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fddg.13706","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.13706","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T12:51:57Z","timestamp":1694695917000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.13706"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11,27]]},"references-count":55,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1111\/ddg.13706"],"URL":"https:\/\/doi.org\/10.1111\/ddg.13706","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,11,27]]},"assertion":[{"value":"2018-07-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-09-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-11-27","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}