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There has also been an uptick in the incidence of non\u2010notifiable STIs such as gonorrhea and infections caused by <jats:italic>Chlamydia trachomatis<\/jats:italic> and <jats:italic>Mycoplasma genitalium<\/jats:italic>. A key factor in the spread of these infections is their varied clinical presentation, which includes urogenital, pharyngeal and rectal involvement as well as a large number of asymptomatic cases. New real\u2010time multiplex PCR methods allow for rapid and targeted detection of STI pathogens. The most common bacterial STI is urogenital chlamydial infection caused by serovars D\u2013K, which affects young adults in particular. Lymphogranuloma venereum (LGV) caused by L serovars often presents as chlamydial proctitis. In recent years, <jats:italic>Neisseria (N.) gonorrhoeae<\/jats:italic> has shown a significant development of resistance, with high\u2010level monoresistance and multiresistance to antibiotics commonly used for treatment. It is therefore imperative that sensitivity testing of <jats:italic>N. gonorrhoeae<\/jats:italic> be performed in addition to nucleic acid amplification tests (NAATs). Increased drug resistance has also been observed for <jats:italic>Mycoplasma genitalium<\/jats:italic>, a fact that complicates treatment.<\/jats:p>","DOI":"10.1111\/ddg.13804","type":"journal-article","created":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T14:45:30Z","timestamp":1553784330000},"page":"287-315","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Bacterial sexually transmitted infections"],"prefix":"10.1111","volume":"17","author":[{"given":"Susanne","family":"Buder","sequence":"first","affiliation":[{"name":"German Reference Laboratory for Gonococci Department of Dermatology and Venerology  Vivantes Hospital Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Sch\u00f6fer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology University Medical Center  Frankfurt am Main Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Meyer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology St. Josef Hospital Ruhr University  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviane","family":"Bremer","sequence":"additional","affiliation":[{"name":"Division of Infectious Disease Epidemiology Robert Koch Institute  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter K.","family":"Kohl","sequence":"additional","affiliation":[{"name":"German Reference Laboratory for Gonococci Department of Dermatology and Venerology  Vivantes Hospital Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriane","family":"Skaletz\u2010Rorowski","sequence":"additional","affiliation":[{"name":"WIR \u201cWalk In Ruhr\u201c competence network HIV\/AIDS, Center for Sexual Health and Medicine Department of Dermatology Venereology and Allergology Ruhr University  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Brockmeyer","sequence":"additional","affiliation":[{"name":"WIR \u201cWalk In Ruhr\u201c competence network HIV\/AIDS, Center for Sexual Health and Medicine Department of Dermatology Venereology and Allergology Ruhr University  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,28]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"WHO.Report on global sexually transmitted infection surveillance. 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