{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T04:05:23Z","timestamp":1792555523757,"version":"4.5.0"},"reference-count":169,"publisher":"Wiley","issue":"S7","license":[{"start":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T00:00:00Z","timestamp":1574035200000},"content-version":"vor","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and rationale<\/jats:title>\n                    <jats:p>Xerosis cutis (also referred to as xeroderma, dry skin, asteatosis) affects more than 10 million individuals in Germany. It is among the most common dermatological diagnoses and a cardinal symptom of many dermatological, internal and neurological diseases. Even though it has been established that basic skin care plays a significant role in the management of patients with xerosis cutis, there are as yet no evidence\u2010based algorithms for diagnosis and treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The present position paper provides physicians across all specialties with a practical, symptom\u2010based approach to the prevention, diagnosis and treatment of xerosis cutis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Within a structured decision\u2010making process, a panel of experienced dermatologists first defined questions relevant to everyday clinical practice, which were then addressed by a systematic review of the literature. Based on the evidence available as well as expert consensus, diagnostic and treatment algorithms were subsequently developed and agreed upon.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Xerosis cutis is generally diagnosed on clinical grounds. Possible trigger factors must be avoided, and comorbidities should be adequately and specifically treated. Suitable skin care products should be chosen with a view to improving skin hydration and restoring its barrier function. They should therefore contain both rehydrating and lipid\u2010replenishing components. The \u201cdrier\u201d the skin appears, the greater the lipid content should be (preferably using water\u2010in\u2010oil formulations). The choice of ingredients is based on a patient's individual symptoms, such as scaling (e.g., urea), fissures\/rhagades (e.g., urea or dexpanthenol), erythema (e.g., licochalcone A) and pruritus (e.g., polidocanol). Other factors to be considered include the site affected and patient age. Ingredients or rather combinations thereof for which there is good clinical evidence should be preferentially used. The best evidence by far is available for urea, whose efficacy in the treatment of xerosis is further enhanced by combining it with other natural moisturizing components and ceramides. The \u201cxerosimeter\u201d is a tool developed in an effort to facilitate patient management and for training purposes. It not only includes practical tools for diagnosis and follow\u2010up but also a classification of ingredients and a structured treatment algorithm.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The structured symptom\u2010 and evidence\u2010based approach proposed herein contains a road map for diagnosis and treatment of xerosis cutis. It aims to raise awareness in terms of prevention and early treatment of this condition and may thus improve quality of life and prevent potential sequelae.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ddg.13906","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T06:39:46Z","timestamp":1574059186000},"page":"3-33","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":109,"title":["Diagnosis and treatment of xerosis cutis \u2013 a position paper"],"prefix":"10.1111","volume":"17","author":[{"given":"Matthias","family":"Augustin","sequence":"first","affiliation":[{"name":"Hamburg\u2010Eppendorf University Medical Center Institute for Healthcare Research in Dermatology and Nursing (IVDP)  Martinistr. 52 20246 Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dagmar","family":"Wilsmann\u2010Theis","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology University Medical Center, Friedrich Wilhelm University  Sigmund Freud Str. 25 53105 Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"K\u00f6rber","sequence":"additional","affiliation":[{"name":"Office\u2010based Dermatologist  R\u00fcttenscheider Str. 143 45130 Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Kerscher","sequence":"additional","affiliation":[{"name":"University of Hamburg, Division of Cosmetic Sciences  Papendamm 21 20146 Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6tz","family":"Itschert","sequence":"additional","affiliation":[{"name":"Office\u2010based Dermatologist  Am Rathaus 2a 25421 Pinneberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Dippel","sequence":"additional","affiliation":[{"name":"MD medscript &amp; consult  Am Kuhtriftberg 21 67098 Bad D\u00fcrkheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Staubach","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center, Johannes Gutenberg University  Langenbeckstr. 1 55131 Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,11,18]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"KreskenJ DanielsR Arens\u2010CorellM.Leitlinie der GD Gesellschaft f\u00fcr Dermopharmazie e.V.: Dermokosmetika zur Reinigung und Pflege trockener Haut. 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