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Typical, albeit not specific histological findings include \u2018flame figures\u2019, which are caused by the accumulation of cationic proteins released by eosinophils and subsequent collagen denaturation.<\/jats:p><jats:p>\u201cClassic\u201d eosinophilic dermatoses include eosinophilic cellulitis (Wells syndrome), granuloma faciale, eosinophilic fasciitis (Shulman syndrome) and eosinophilic folliculitis (Ofuji disease). In addition, there is a multitude of skin diseases that present with varying degrees of eosinophilic infiltration. These include atopic dermatitis, bullous pemphigoid, urticaria, allergic contact dermatitis, prurigo nodularis, arthropod bite reaction, parasitic infections, and drug hypersensitivity. Even though these disorders share a common characteristic (tissue eosinophilia), they differ greatly in their clinical presentation.<\/jats:p>","DOI":"10.1111\/ddg.13943","type":"journal-article","created":{"date-parts":[[2019,9,28]],"date-time":"2019-09-28T04:11:46Z","timestamp":1569643906000},"page":"1039-1051","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Eosinophilic dermatoses"],"prefix":"10.1111","volume":"17","author":[{"given":"Melanie","family":"Peckruhn","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7696-3274","authenticated-orcid":false,"given":"Peter","family":"Elsner","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital  Jena 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