{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T20:26:59Z","timestamp":1785356819976,"version":"3.55.0"},"reference-count":124,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T00:00:00Z","timestamp":1571616000000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Epicutaneous patch testing is the diagnostic standard for the detection of allergic contact dermatitis. The present guidelines are aimed at residents and board\u2010certified physicians in the fields of dermatology and allergology as well as other medical specialties involved in establishing the indication for patch testing and its execution in patients with contact dermatitis and other forms of delayed\u2010type hypersensitivity. The target audience also includes other health care providers and insurance funds.<\/jats:p><jats:p>Based on a systematic literature search and a formal consensus process (S3), the guidelines were developed by dermatologists in collaboration with pediatricians, occupational medicine physicians, nursing staff as well as patient representatives. The systematic methodological approach and appraisal of evidence upon which the recommendations are based are outlined in a separate method report that also contains evidence tables.<\/jats:p><jats:p>The guidelines address general aspects of patch testing as well as medicolegal issues. The recommendations given relate to topics such as the indication for patch testing, informed patient consent, as well as the choice of test substances, test chambers and test site, duration of exposure, reading times and interpretation of test reactions. Furthermore, recommendations are provided with respect to endogenous and exogenous factors, specific patient groups (children, pregnant women, immunosuppressed individuals) as well as possible risks and adverse events associated with patch testing using contact allergens.<\/jats:p><jats:p><jats:italic>Note<\/jats:italic>: This publication is part\u00a01 of the short version of the S3\u00a0guidelines for \u201cEpicutaneous patch testing using contact allergens and drugs\u201d (registry no. 013 \u2013 018; date: March 20, 2019; valid until December 31, 2021). Part 2 of the short version will be published in the next issue. The long version of these guidelines can be accessed at<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.awmf.org\">www.awmf.org<\/jats:ext-link>. The method report is available as online publication (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/www.awmf.org\/leitlinien\/detail\/ll\/013-018.html\">https:\/\/www.awmf.org\/leitlinien\/detail\/ll\/013\u2010018.html<\/jats:ext-link>) and contains the evidence tables in its appendix.<\/jats:p>","DOI":"10.1111\/ddg.13956","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T08:56:41Z","timestamp":1571648201000},"page":"1076-1093","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":110,"title":["S3 guidelines: Epicutaneous patch testing with contact allergens and drugs \u2013 Short version, Part 1"],"prefix":"10.1111","volume":"17","author":[{"given":"Vera","family":"Mahler","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital Erlangen Friedrich\u2010Alexander University Erlangen\u2010N\u00fcrnberg Erlangen Germany"},{"name":"Paul\u2010Ehrlich\u2010Institut Langen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Nast","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2010 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin, Humboldt University of Berlin, and Berlin Institute of Health Department of Dermatology Venereology und Allergology Division of Evidence\u2010based Medicine (dEBM) Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Dresden Technical University Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Detlef","family":"Becker","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jochen","family":"Brasch","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology und Allergology University Medical Center Kiel Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristine","family":"Breuer","sequence":"additional","affiliation":[{"name":"Dermatology Practice (Dermatologie Reinbek) Reinbek Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinrich","family":"Dickel","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology und Allergology St. Josef Hospital Ruhr University Bochum Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Drexler","sequence":"additional","affiliation":[{"name":"Institute for Occupational Social and Environmental Medicine Friedrich\u2010\u00adAlexander University Erlangen\u2010N\u00fcrnberg Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Elsner","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Jena Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johannes","family":"Geier","sequence":"additional","affiliation":[{"name":"Information Network of Departments of Dermatology (IVDK) Institute at the University Medical Centre G\u00f6ttingen G\u00f6ttingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swen Malte","family":"John","sequence":"additional","affiliation":[{"name":"Institute for Interdisciplinary Dermatological Prevention and Rehabilitation (iDerm) University of Osnabr\u00fcck Osnabr\u00fcck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burkhard","family":"Kreft","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Martin Luther University Halle\u2010Wittenberg Halle (Saale) Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arno","family":"K\u00f6llner","sequence":"additional","affiliation":[{"name":"Dermatology Group Practice Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Merk","sequence":"additional","affiliation":[{"name":"Professor of Dermatology\u00a0and\u00a0Allergology Former Chairman of the Department of Dermatology RWTH University Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hagen","family":"Ott","sequence":"additional","affiliation":[{"name":"Division of Pediatric Dermatology and Allergology Children's Hospital Auf der Bult Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Pleschka","sequence":"additional","affiliation":[{"name":"German Allergy and Asthma Foundation (Deutscher Allergie\u2010 und Asthmabund e.V.) 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