{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T04:22:16Z","timestamp":1771474936918,"version":"3.50.1"},"reference-count":48,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T00:00:00Z","timestamp":1590710400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2020,6]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Perianal dermatitis (anal eczema, perianal eczema) is one of the most common proctological conditions. It may occur as a sequela or a presenting symptom of various proctological, dermatological, allergic or pathogen\u2010induced disorders. The three main types of anal eczema are irritant\u2010toxic, atopic and allergic contact dermatitis. Adequate and successful treatment requires a comprehensive diagnostic workup to determine disease etiology and includes treatment\/elimination of causative factors as well as nonpharmacological interventions (avoidance of aggravating factors). In addition, adjuvant topical anti\u2010inflammatory and\/or specific symptomatic treatment may be required. The present guidelines contain recommendations for the diagnostic and therapeutic management of perianal dermatitis. Target users of these guidelines are clinicians in the fields of dermatology and proctology, as well as all other specialties involved in the management of patients with perianal dermatitis, both in hospital and office\u2010based settings.<\/jats:p>","DOI":"10.1111\/ddg.14125","type":"journal-article","created":{"date-parts":[[2020,5,29]],"date-time":"2020-05-29T15:30:54Z","timestamp":1590766254000},"page":"648-657","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["German S1 guidelines for the diagnosis and treatment of perianal dermatitis (anal eczema)"],"prefix":"10.1111","volume":"18","author":[{"given":"Gerhard","family":"Weyandt","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergology Klinikum Bayreuth  Bayreuth Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Breitkopf","sequence":"additional","affiliation":[{"name":"Enddarmpraxis im Franziskus Carr\u00e9  M\u00fcnster Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo Niklas","family":"Werner","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology und Allergology Division of Evidence\u2010based Medicine (dEBM) Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin Humboldt University of Berlin and Berlin Institute of Health  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Zidane","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology und Allergology Division of Evidence\u2010based Medicine (dEBM) Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin Humboldt University of Berlin and Berlin Institute of Health  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Furtw\u00e4ngler","sequence":"additional","affiliation":[{"name":"Praxisklinik 2000 Proktologische Praxis Freiburg Freiburg im Breisgau  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Jongen","sequence":"additional","affiliation":[{"name":"Proktologische Praxis Kiel  Kiel Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Rothhaar","sequence":"additional","affiliation":[{"name":"Die Hautambulanz  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Schaefer","sequence":"additional","affiliation":[{"name":"Hautarztpraxis Dr. Daniel Schaefer  \u00d6hringen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernhard","family":"Lenhard","sequence":"additional","affiliation":[{"name":"Praxis f\u00fcr Enddarmerkrankungen  Heidelberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,29]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10354-004-0046-3"},{"key":"e_1_2_10_3_1","first-page":"366","article-title":"Pruritus ani","volume":"39","author":"MacLean J","year":"2010","journal-title":"Aust Fam Physician"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-009-1812-3"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00508-006-0529-x"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-004-0700-0"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0000000000000274"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2005.05763.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-103768"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-47262-0_20"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1994.tb00696.x"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/WON.0b013e31822272d9"},{"key":"e_1_2_10_13_1","first-page":"46","article-title":"Incontinence\u2010associated skin damage in nursing home residents: a secondary analysis of a prospective, multicenter study","volume":"52","author":"Zimmaro Bliss D","year":"2006","journal-title":"Ostomy Wound Manage"},{"key":"e_1_2_10_14_1","first-page":"12","article-title":"Haemorrhoidal disease: the dermatological differential diagnoses of symptoms and anal findings","volume":"31","author":"Weyandt GH","year":"2010","journal-title":"Aliment Pharmacol Ther"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.04.042"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.5021\/ad.2010.22.2.125"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(96)00119-9"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.5402\/2012\/408769"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-836945"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00958.x"},{"key":"e_1_2_10_21_1","first-page":"649","article-title":"Allergic contact dermatitis in patients with anogenital complaints","volume":"45","author":"Bauer A","year":"2000","journal-title":"J Reprod Med"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1991.tb01669.x"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-0960.2001.00493.x"},{"key":"e_1_2_10_24_1","first-page":"85","article-title":"Allergisches Kontaktekzem durch Euxyl K 400 in feuchtem Toilettenpapier","volume":"19","author":"Komericki P","year":"1996","journal-title":"Allergologie"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2007.01188.x"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1989.tb04707.x"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.144.6.749"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1159\/000321065"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2006.00919.x"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1097\/DER.0b013e31826e443c"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.5414\/ALX02073"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.287.6404.1528"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.287.6386.159"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2012.04635.x"},{"key":"e_1_2_10_35_1","first-page":"562","article-title":"[Anal hygiene in perianal skin diseases \u2013 compatibility of water moist and dry toilet paper]","volume":"200","author":"Bruhl W","year":"1998","journal-title":"Zentralbl Hyg Umweltmed"},{"key":"e_1_2_10_36_1","first-page":"1","article-title":"Practical management strategies for diaper dermatitis","volume":"11","author":"Humphrey S","year":"2006","journal-title":"Skin Therapy Lett"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1159\/000215593"},{"key":"e_1_2_10_38_1","first-page":"23","article-title":"[Clinical evaluation of the efficacy and tolerability of the \u201cNoAll Bimbi Pasta Trattante\u201d barrier cream in napkin dermatitis]","volume":"59","author":"Patrizi A","year":"2007","journal-title":"Minerva Pediatr"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.2829"},{"key":"e_1_2_10_40_1","first-page":"385","article-title":"The treatment of haemorrhoidal symptom complexes","volume":"35","author":"Chlebraov C.","year":"1985","journal-title":"Therapiewoche"},{"key":"e_1_2_10_41_1","first-page":"918","article-title":"Studies on the local tolerance and clinical efficacy of Doloproct Creme in the perianal area","volume":"14","author":"Herms E.","year":"1988","journal-title":"Akt Dermatol"},{"key":"e_1_2_10_42_1","first-page":"918","article-title":"[The symptomatic therapy of hemorrhoids and anal eczema \u2013 a report of experiences from proctology practice]","volume":"79","author":"Neiger A","year":"1990","journal-title":"Schweiz Rundsch Med Prax"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06327.x"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09345.x"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-007-0325-8"},{"key":"e_1_2_10_46_1","first-page":"515","article-title":"Local treatment of hemorrhoidal disease and perianal eczema. Meta\u2010analysis of the efficacy and safety of an Escherichia coli culture suspension alone or in combination with hydrocortisone","volume":"52","author":"Wienert V","year":"2002","journal-title":"Arzneimittelforschung"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1999.00757.x"},{"key":"e_1_2_10_48_1","first-page":"177","article-title":"[Analytical review of multicenter studies with polycresulene for hemorrhoidal pathologies]","volume":"30","author":"Espinosa DJ","year":"2000","journal-title":"Acta Gastroenterol Latinoam"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijcp.12457"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fddg.14125","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14125","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ddg.14125","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14125","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T10:52:29Z","timestamp":1692960749000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.14125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,29]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,6]]}},"alternative-id":["10.1111\/ddg.14125"],"URL":"https:\/\/doi.org\/10.1111\/ddg.14125","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,29]]},"assertion":[{"value":"2019-06-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}