{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T05:23:04Z","timestamp":1761110584851,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,2,12]],"date-time":"2021-02-12T00:00:00Z","timestamp":1613088000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>A dramatic rise in the incidence rates of basal cell carcinoma (BCC) in young women has been reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objectives<\/jats:title><jats:p>We investigate potential risk factors (RF) for sporadic BCC in young patients and the current distribution of such RF in the general population of Catalonia, comparing the differences among men and women.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>A case\u2010control study was performed, 69 BCCs diagnosed in patients \u2264\u00a045 years of age vs. 69 healthy\u00a0controls. Afterward, 1,078 participants from the general population completed an RF questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Repeated sunburns were more frequent in instances of early\u2010onset BCC in covered skin than in sun\u2010exposed skin (<jats:italic>P<\/jats:italic>\u00a0 = \u00a00.029). In the general population, 39.1\u00a0% of participants reported sunbed use (50.1\u00a0% in women, 10.9\u00a0% in men). Sunbed use was the only relevant RF more predominant in women than men, favoring the trend to female predominance of BCCs above other RF. Additionally, we found a significant trend in young participants for reduced sunbed use (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.001), although they had the same percentage of repeated sunburns. Repeated sunburns are the most relevant RF for early\u2010onset BCCs that can be targeted in prevention campaigns.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We should be aware of the more relevant RF for early\u2010onset BCCs and their distribution among the general population to address preventive campaigns.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ddg.14390","type":"journal-article","created":{"date-parts":[[2021,2,14]],"date-time":"2021-02-14T04:57:14Z","timestamp":1613278634000},"page":"364-371","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Risk factors for early\u2010onset basal cell carcinomas and the trend towards their female predominance"],"prefix":"10.1111","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9911-6924","authenticated-orcid":false,"given":"Clara","family":"Matas\u2010Nadal","sequence":"first","affiliation":[{"name":"IRB Lleida  Lleida Catalunya Spain"},{"name":"Dermatology Department Corporaci\u00f3 de Salut de la Selva i el Maresme  Girona Spain"},{"name":"Dermatology Department Hospital Universitari Arnau de Vilanova de Lleida  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Sagrist\u00e0","sequence":"additional","affiliation":[{"name":"Dermatology Department Corporaci\u00f3 de Salut de la Selva i el Maresme  Girona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"G\u00f3mez\u2010Arbon\u00e9s","sequence":"additional","affiliation":[{"name":"Departament de Medicina Universitat de Lleida  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Sobrino Bermejo","sequence":"additional","affiliation":[{"name":"Dermatology Department Hospital Universitari Arnau de Vilanova de Lleida  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep Manel","family":"Fern\u00e1ndez\u2010Armenteros","sequence":"additional","affiliation":[{"name":"IRB Lleida  Lleida Catalunya Spain"},{"name":"Dermatology Department Hospital Universitari Arnau de Vilanova de Lleida  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan","family":"\u00c0ngel Bald\u00f3","sequence":"additional","affiliation":[{"name":"IRB Lleida  Lleida Catalunya Spain"},{"name":"Dermatology Department Hospital Universitari Arnau de Vilanova de Lleida  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josep Manel","family":"Casanova Seuma","sequence":"additional","affiliation":[{"name":"IRB Lleida  Lleida Catalunya Spain"},{"name":"Dermatology Department Hospital Universitari Arnau de Vilanova de Lleida  Lleida Spain"},{"name":"Departament de Medicina Universitat de Lleida  Lleida Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1690-1618","authenticated-orcid":false,"given":"Rafael","family":"Aguayo Ortiz","sequence":"additional","affiliation":[{"name":"IRB Lleida  Lleida Catalunya Spain"},{"name":"Dermatology Department Hospital Universitari Arnau de Vilanova de Lleida  Lleida 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