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For localized forms, symptomatic, topical therapy options are currently still the primary choice. Of particular interest is the new option of topical therapy with diacerein 1\u00a0% cream. In the case of a pronounced clinical picture with extracutaneous organ involvement, multidisciplinary management is required.<\/jats:p><jats:p>In the future, new forms of therapy such as autologous epidermal stem cell transplantation and gene therapeutic procedures may be applied. Human genetic counselling is indispensable.<\/jats:p>","DOI":"10.1111\/ddg.14446","type":"journal-article","created":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T07:57:30Z","timestamp":1620287850000},"page":"983-986","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Epidermolysis bullosa dystrophica pretibialis \u2013 Clinical snapshot and management of a rare orphan disease"],"prefix":"10.1111","volume":"19","author":[{"given":"Lisa Marlen","family":"Will","sequence":"first","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Saarland University Medical Center  Homburg\/Saar Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Reichrath","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Saarland University Medical Center  Homburg\/Saar Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Vogt","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Saarland University Medical Center  Homburg\/Saar Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-49544-5_48"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2016.2473"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18921"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.01.903"},{"key":"e_1_2_5_6_1","volume-title":"Dystrophic epidermolysis bullosa. 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