{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T13:37:25Z","timestamp":1778852245244,"version":"3.51.4"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,5,5]],"date-time":"2021-05-05T00:00:00Z","timestamp":1620172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Ocular manifestations of syphilis with visual impairment symptoms may occur already at the stage of secondary syphilis. They may also be the only manifestation of syphilis and mimic other diseases of the eye. Therefore, in all patients with uveitis, optic neuritis, optic atrophy, acute ocular muscle paresis, or loss of visual acuity, syphilis infection should be ruled out, even if the medical history does not initially raise suspicion.<\/jats:p><jats:p>Ocular involvement should be treated as neurosyphilis. Delayed diagnosis and inadequate therapy are often associated with irreversible consequences for the affected patient. As with any syphilis infection, HIV infection should be considered and excluded, especially in the case of ocular manifestations.<\/jats:p>","DOI":"10.1111\/ddg.14464","type":"journal-article","created":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T06:59:36Z","timestamp":1620284376000},"page":"987-991","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Ocular syphilis \u2013 a case series of four patients"],"prefix":"10.1111","volume":"19","author":[{"given":"Stephanie","family":"Jahnke","sequence":"first","affiliation":[{"name":"University Hospital and Clinic for Dermatology and Venereology University Hospital Halle (Saale) of Martin Luther University Halle\u2010Wittenberg  Halle (Saale) Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cord","family":"Sunderk\u00f6tter","sequence":"additional","affiliation":[{"name":"University Hospital and Clinic for Dermatology and Venereology University Hospital Halle (Saale) of Martin Luther University Halle\u2010Wittenberg  Halle (Saale) Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danica","family":"Lange","sequence":"additional","affiliation":[{"name":"University Hospital and Clinic for Dermatology and Venereology University Hospital Halle (Saale) of Martin Luther University Halle\u2010Wittenberg  Halle (Saale) Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricarda","family":"Wienrich","sequence":"additional","affiliation":[{"name":"University Hospital and Clinic for Ophthalmology University Hospital Halle (Saale) of Martin\u00a0Luther University Halle\u2010Wittenberg  Halle (Saale) Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burkhard","family":"Kreft","sequence":"additional","affiliation":[{"name":"University Hospital and Clinic for Dermatology and Venereology University Hospital Halle (Saale) of Martin Luther University Halle\u2010Wittenberg  Halle (Saale) Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,5,5]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"RKI Syphilis in Deutschland im Jahr 2018 \u2013 Anstieg der Vorjahre stagniert auf hohem Niveau. Epidemiologisches Bulletin 50\/2019. Available from:https:\/\/www.rki.de\/DE\/Content\/Infekt\/EpidBull\/Archiv\/2019\/Ausgaben\/50_19.pdf?__blob=publicationFile[Last accessed February 26 2021]."},{"issue":"3","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/ddg.13804_g","article-title":"Bakterielle sexuell \u00fcbertragbare Infektionen","volume":"17","author":"Buder S","year":"2019","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_10_4_1","unstructured":"JansenK.AWMF\u2010Leitlinie 2020. Reg.\u2010Nr. 059\u2010002 Diagnostik und Therapie der Syphilis. Epidemiologie Kap. 4 S. 2020; 6\u201313. 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