{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:59:02Z","timestamp":1747184342102,"version":"3.40.5"},"reference-count":15,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T00:00:00Z","timestamp":1626825600000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:p>Okul\u00e4re Manifestationen einer Syphilis mit Visus\u2010beeintr\u00e4chtigenden Beschwerdebildern k\u00f6nnen sich bereits im Sekund\u00e4rstadium der Erkrankung ereignen. Sie k\u00f6nnen auch die einzige Manifestation einer Syphilis sein und andere Erkrankungen des Auges imitieren. Daher sollte bei allen Patienten mit Uveitis, Optikusneuritis, Optikusatrophie, akut aufgetretener Augenmuskelparese beziehungsweise bei ungekl\u00e4rtem Visusverlust eine Syphilisinfektion ausgeschlossen werden. Dies gilt auch, wenn die anamnestischen Angaben zun\u00e4chst keine Verdachtsmomente liefern.<\/jats:p><jats:p>Die okul\u00e4re Manifestation der Erkrankung sollte wie eine Neurosyphilis behandelt werden. Eine verz\u00f6gerte Diagnosestellung und inad\u00e4quate Therapie gehen vielfach mit irreversiblen Folgen f\u00fcr den betroffenen Patienten einher. Grunds\u00e4tzlich ist bei Auftreten einer Syphilis immer das Vorliegen einer assoziierten HIV\u2010Infektion zu \u00fcberpr\u00fcfen.<\/jats:p>","DOI":"10.1111\/ddg.14464_g","type":"journal-article","created":{"date-parts":[[2021,7,21]],"date-time":"2021-07-21T07:49:21Z","timestamp":1626853761000},"page":"987-992","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Okul\u00e4re Syphilis \u2013 eine Fallserie von vier Patienten"],"prefix":"10.1111","volume":"19","author":[{"given":"Stephanie","family":"Jahnke","sequence":"first","affiliation":[{"name":"Universit\u00e4tsklinik und Poliklinik f\u00fcr Dermatologie und Venerologie Universit\u00e4tsklinikum Halle (Saale) der Martin\u2010Luther\u2010Universit\u00e4t Halle\u2010 Wittenberg  Halle (Saale)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2929-145X","authenticated-orcid":false,"given":"Cord Sunderk\u00f6tter Danica","family":"Lange","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik und Poliklinik f\u00fcr Dermatologie und Venerologie Universit\u00e4tsklinikum Halle (Saale) der Martin\u2010Luther\u2010Universit\u00e4t Halle\u2010 Wittenberg  Halle (Saale)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricarda","family":"Wienrich","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik und Poliklinik f\u00fcr Augenheilkunde Universit\u00e4tsklinikum Halle (Saale) der Martin\u2010Luther\u2010Universit\u00e4t Halle\u2010Wittenberg  Halle (Saale)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burkhard","family":"Kreft","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik und Poliklinik f\u00fcr Dermatologie und Venerologie Universit\u00e4tsklinikum Halle (Saale) der Martin\u2010Luther\u2010Universit\u00e4t Halle\u2010 Wittenberg  Halle (Saale)"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,7,21]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"RKI Syphilis in Deutschland im Jahr 2018 \u2013 Anstieg der Vorjahre stagniert auf hohem Niveau. Epidemiologisches Bulletin 50\/2019. Available from:https:\/\/www.rki.de\/DE\/Content\/Infekt\/EpidBull\/Archiv\/2019\/Ausgaben\/50_19.pdf?__blob=publicationFile[Last accessed February 26 2021]."},{"issue":"3","key":"e_1_2_10_3_1","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/ddg.13804_g","article-title":"Bakterielle sexuell \u00fcbertragbare Infektionen","volume":"17","author":"Buder S","year":"2019","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_10_4_1","unstructured":"JansenK.AWMF\u2010Leitlinie 2020. Reg.\u2010Nr. 059\u2010002 Diagnostik und Therapie der Syphilis. Epidemiologie Kap (2020) 4 S. 6\u201313. 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