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Obwohl LP klinisch gut definiert ist, stellt die Erkrankung immer noch eine therapeutische Herausforderung dar. Insbesondere f\u00fcr LP\u2010Typen an Schleimhaut oder Kopfhaut, die oft rezidivieren und nicht auf Behandlungen ansprechenden, fehlen nach wie vor wirksame Therapien. LP bedingt eine sehr hohe psychosoziale Belastung bei den Betroffenen. Neue Erkenntnisse zur LP\u2010Pathogenese zeigen m\u00f6gliche Angriffspunkte f\u00fcr Medikamente auf und ebnen so den Weg f\u00fcr k\u00fcnftige Therapien. 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