{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:47Z","timestamp":1787014067664,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T00:00:00Z","timestamp":1636070400000},"content-version":"vor","delay-in-days":4,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Dermatomyositis belongs to the rare idiopathic, inflammatory myositis group. A previously postulated link between some cases of dermatomyositis and malignancy has been established in recent years. Criteria suggestive of a malignancy association are still being explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>We retrospectively analyzed data from 63 patients with dermatomyositis over a period of 15 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The following criteria argue for cancer\u2010associated dermatomyositis: older age (&gt;\u00a052 years [\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001], &gt;\u00a065 years [\n                      <jats:italic>P<\/jats:italic>\n                      = 0.002], \u2265\u00a075 years [\n                      <jats:italic>P<\/jats:italic>\n                      = 0.002]), shorter time between manifestation and diagnosis of dermatomyositis (malignancy group: 59 days vs. non\u2010malignancy group: 137 days [\n                      <jats:italic>P<\/jats:italic>\n                      = 0.022]), typical skin involvement such as Gottron sign (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.045), centrofacial erythema (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.036) and typical erythema on the upper arms and forearms (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.019), oropharyngeal involvement (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.015) and increased ALT (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.031). The following criteria argue for non\u2010cancer\u2010associated dermatomyositis: younger age (\u2264\u00a052 years [\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001], 40\u201365 years [\n                      <jats:italic>P<\/jats:italic>\n                      = 0.045]) and pruritus (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.026).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The aforementioned criteria have been documented in the literature, but reported findings are heterogenous concerning the suitability of their markers for malignancy association. Small study populations, few prospective controlled studies, summarization of different forms of myositis and inconsistent use nomenclature contribute to biased results. Our study aims to make an important contribution toward the identification of risk factors in cancer\u2010associated dermatomyositis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ddg.14566","type":"journal-article","created":{"date-parts":[[2021,11,5]],"date-time":"2021-11-05T10:04:57Z","timestamp":1636106697000},"page":"1601-1611","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Characteristics of dermatomyositis patients with and without associated malignancy"],"prefix":"10.1111","volume":"19","author":[{"given":"Julia","family":"Lauinger","sequence":"first","affiliation":[{"name":"Department of Dermatology University of T\u00fcbingen  T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamran","family":"Ghoreschi","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Charit\u00e9\u2013 Universit\u00e4tsmedizin Berlin corporate member of Freie Universit\u00e4t Berlin Humboldt\u2010Universit\u00e4t zu Berlin and Berlin Institute of Health  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Volc","sequence":"additional","affiliation":[{"name":"Department of Dermatology University of T\u00fcbingen  T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-015-3659-0"},{"key":"e_1_2_7_3_1","first-page":"438","article-title":"Dermatomyositis and polymyositis associated with malignancy: a 21\u2010year retrospective study","volume":"35","author":"Andras C","year":"2008","journal-title":"J 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