{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:32:07Z","timestamp":1787499127439,"version":"build-2736575974"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T00:00:00Z","timestamp":1637798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and objectives<\/jats:title>\n                    <jats:p>Significant psychological morbidity exists in patients with active pemphigus. Pemphigus being a chronic disease, psychological morbidity may exist in pemphigus patients in remission as well. The objectives of the study were to assess the psychological morbidity in pemphigus patients in clinical remission and to correlate it with clinico\u2010demographic parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>Pemphigus patients in clinical remission were consecutively included and were asked to respond to the Hindi\/English version of Patient Health Questionnaire (PHQ\u20109), Generalized Anxiety Disorder (GAD\u20107) and panic disorder module of PHQ.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 107 patients recruited, 41 (38.3\u00a0%, 95\u00a0% CI: 29.1\u201348.2\u00a0%) patients were found to have either depression (33 [30.8\u00a0%, 95\u00a0% CI: 22.2\u201340.5\u00a0%]) or anxiety (38 [35.5\u00a0%, 95\u00a0% CI: 26.5\u201345.4\u00a0%] syndrome based on cut\u2010offs of PHQ\u20109 score and GAD\u20107 score, respectively. Number of patients with mild, moderate and moderately severe\/severe depression syndrome were 26 (24.3\u00a0%, 95\u00a0% CI: 17.2\u201333.2\u00a0%), 7 (6.5\u00a0%, 95\u00a0% CI: 0.3\u201312.9\u00a0%) and 0 respectively and patients with mild, moderate, severe anxiety syndrome were 29 (27.1\u00a0%, 95\u00a0% CI: 19.6\u201336.2\u00a0%), 9 (8.4\u00a0%, 95\u00a0% CI: 4.5\u201315.2\u00a0%) and 0 respectively. Patients with anxiety or depression syndrome had significantly higher clinical disease activity in the past, number of days spent in dermatology inpatient and significantly shorter clinical remission at the time of assessment as compared to those without these symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Significant burden of mild\/moderate depression or anxiety syndrome associated with past severity of disease and shorter duration of clinical remission was found.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ddg.14605","type":"journal-article","created":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T09:25:05Z","timestamp":1637832305000},"page":"26-33","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Psychological morbidity in pemphigus patients in clinical remission and its relation with clinico\u2010demographic parameters"],"prefix":"10.1111","volume":"20","author":[{"given":"Dipankar","family":"De","sequence":"first","affiliation":[{"name":"Department of Dermatology Venereology and Leprology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheetanshu","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Leprology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Handa","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Leprology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Leprology Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shubh Mohan","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Postgraduate Institute of Medical Education and Research  Chandigarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,25]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2005.01139.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1111\/ddg.13637","article-title":"Diagnosis of autoimmune bullous diseases","volume":"16","author":"Van Beek N","year":"2018","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_7_4_1","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1111\/ddg.13688","article-title":"Bullous autoimmune dermatoses","volume":"16","author":"Hofmann SC","year":"2018","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5154.87151"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2011.01382.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.09.014"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08481.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0151-9638(05)79276-0"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajp.2012.10.005"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12836"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.282.18.1737"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.106580"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.111.000049"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.01.012"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.18203\/2394-6040.ijcmph20171313"},{"key":"e_1_2_7_18_1","first-page":"4","article-title":"Introducing a novel Autoimmune Bullous Skin Disorder Intensity Score (ABSIS) in pemphigus","volume":"17","author":"Pfutze M","year":"2007","journal-title":"Eur J Dermatol"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2010.10.030"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-015-0965-z"},{"key":"e_1_2_7_21_1","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1111\/ddg.13389","article-title":"High\u2010dose intravenous immunoglobulins for the treatment of dermatological autoimmune diseases","volume":"15","author":"Hoffmann JHO","year":"2017","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_7_22_1","first-page":"516","article-title":"S2k guidelines for the treatment of pemphigus vulgaris\/foliaceus and bullous pemphigoid: 2019 update","volume":"18","author":"Schmidt E","year":"2020","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15658"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/da.22026"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14605","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ddg.14605","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14605","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,26]],"date-time":"2023-08-26T22:17:50Z","timestamp":1693088270000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.14605"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,25]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1111\/ddg.14605"],"URL":"https:\/\/doi.org\/10.1111\/ddg.14605","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,25]]},"assertion":[{"value":"2021-02-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-25","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}