{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,4]],"date-time":"2025-12-04T10:03:18Z","timestamp":1764842598178},"reference-count":57,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T00:00:00Z","timestamp":1652659200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec><jats:title>Hintergrund und Ziele<\/jats:title><jats:p>Ziel dieser Studie war die Untersuchung des Zusammenhangs zwischen Vitiligo und dem metabolischen Syndrom (MetS) sowie dessen relevanten Komponenten.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material und Methoden<\/jats:title><jats:p>Die Datenbanken PubMed, Web of Science, Cochrane Library und Embase wurden von deren Beginn bis zum 30.\u00a0M\u00e4rz 2021 nach relevanten Studien durchsucht. Querschnitts\u2010 und Fall\u2010Kontroll\u2010Studien, die entweder die Pr\u00e4valenz oder die Odds\u2010Ratio [OR] des MetS oder seiner Komponenten bei Vitiligo\u2010Patienten berichteten, wurden eingeschlossen. Die Daten wurden entsprechend der Heterogenit\u00e4t entweder mit einem Zufallseffektmodell oder einem Modell mit festen Effekten gepoolt.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ergebnisse<\/jats:title><jats:p>Es wurden 30 Studien mit insgesamt 28.325 Vitiligo\u2010Patienten eingeschlossen. Signifikante Zusammenh\u00e4nge wurden zwischen Vitiligo und Diabetes mellitus (gepoolte OR, 3,30; 95\u00a0%\u2010Konfidenzintervall [KI], 2,10\u20135,17) sowie zwischen Vitiligo und Adipositas (gepoolte OR, 2,08; 95\u00a0%\u2010KI, 1,40\u20133,11) ermittelt. Die Gesamtpr\u00e4valenz der Hypertonie bei Patienten mit Vitiligo betrug 19,0\u00a0% (95\u00a0%\u2010KI, 2,0\u00a0%\u201336,0\u00a0%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Schlussfolgerungen<\/jats:title><jats:p>Unserer Ergebnisse lassen auf einen Zusammenhang zwischen Vitiligo und Diabetes mellitus sowie Hypertonie schlie\u00dfen. Dermatologen wird empfohlen diese Zusammenh\u00e4nge zu ber\u00fccksichtigen, um potenzielle Begleiterkrankungen bei Vitiligo\u2010Patienten zeitnah zu identifizieren. Zudem wird Vitiligo\u2010Patienten empfohlen, Parameter wie BMI, Blutzuckerspiegel und Blutdruck zu \u00fcberwachen und bei auff\u00e4lligen Ver\u00e4nderungen dieser Parameter unverz\u00fcglich einen Spezialisten zu konsultieren.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ddg.14717_g","type":"journal-article","created":{"date-parts":[[2022,5,17]],"date-time":"2022-05-17T04:54:40Z","timestamp":1652763280000},"page":"629-642","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Zusammenhang zwischen Vitiligo und wichtigen Komponenten des metabolischen Syndroms: eine systematische \u00dcbersicht und Metaanalyse"],"prefix":"10.1111","volume":"20","author":[{"given":"Pan","family":"Kang","sequence":"first","affiliation":[{"name":"Department of Dermatology Xijing Hospital Fourth Military Medical University  Xi'an Shaanxi China"},{"name":"Department of Epidemiology School of Public Health Fourth Military Medical University  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