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Finding the correct diagnosis is essential for selecting an appropriate treatment and can help to reduce the inappropriate use of antibiotics. The guideline committee identified the most relevant differential diagnoses: 1. erysipelas, 2. stasis dermatitis, 3. hyperergic ictus reaction, 4. superficial and deep vein thrombosis, 5. gout, 6. chronic allergic contact dermatitis, and 7. acute toxic or allergic contact dermatitis. Algorithms\/diagnostic pathways, each of which can be broken down into anamnesis, clinical examination, and diagnostics, have been developed for these seven diagnoses. In addition, the guideline group identified over 40 other relevant diagnoses and summarized their characteristics in a table to facilitate further differential diagnoses.<\/jats:p>","DOI":"10.1111\/ddg.14816","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T12:17:16Z","timestamp":1656332236000},"page":"1041-1047","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["S1 guideline: Differential diagnosis of acute and chronic redness of the lower legs"],"prefix":"10.1111","volume":"20","author":[{"given":"Miriam","family":"Zidane","sequence":"first","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Division of Evidence\u2010Based Medicine (dEBM) Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin corporate member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans\u2010Wilfried","family":"Jungkunz","sequence":"additional","affiliation":[{"name":"Practice Dr. Wilfried Jungkunz  Friedberg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit","family":"Kahle","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology University Hospital Schleswig\u2010Holstein Campus L\u00fcbeck  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anya","family":"Miller","sequence":"additional","affiliation":[{"name":"Practice Dr.med. 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