{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T17:39:42Z","timestamp":1788457182388,"version":"build-2803163510"},"reference-count":0,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T00:00:00Z","timestamp":1665964800000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2022,10]]},"abstract":"Summary<\/jats:title>Pruritus is a cross\u2010disciplinary leading symptom of numerous diseases and represents an interdisciplinary diagnostic and therapeutic challenge. In contrast to acute pruritus, chronic pruritus (CP) is a symptom of various diseases that is usually difficult to treat. Scratching and the development of scratch\u2010associated skin lesions can alter the original skin status. In the presence of an itch\u2010scratch\u2010cycle, even secondary diseases such as chronic prurigo can develop. Chronic pruritus leads to considerable subjective suffering of those affected, which can result in restrictions on the health\u2010related quality of life such as sleep disturbances, anxiety, depressiveness, experience of stigmatization and\/or social withdrawal up to clinically relevant psychic comorbidities. Medical care of patients should therefore include (a)<\/jats:italic> interdisciplinary diagnosis and therapy of the triggering underlying disease, (b)<\/jats:italic> therapy of the secondary symptoms of pruritus (dermatological therapy, sleep promotion, in the case of an accompanying or underlying psychological or psychosomatic disease an appropriate psychological\u2010psychotherapeutic treatment) and (c)<\/jats:italic> symptomatic antipruritic therapy. The aim of this interdisciplinary guideline is to define and standardize the therapeutic procedure as well as the interdisciplinary diagnosis of CP. This is the short version of the updated S2k\u2010guideline for chronic pruritus. The long version can be found at www.awmf.org<\/jats:ext-link>.<\/jats:p>","DOI":"10.1111\/ddg.14830","type":"journal-article","created":{"date-parts":[[2022,10,17]],"date-time":"2022-10-17T19:02:36Z","timestamp":1666033356000},"page":"1387-1402","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":54,"title":["S2k guideline: Diagnosis and treatment of chronic pruritus"],"prefix":"10.1111","volume":"20","author":[{"given":"Sonja","family":"St\u00e4nder","sequence":"first","affiliation":[{"name":"Center for Chronic Pruritus (KCP) Department of Dermatology University Hospital M\u00fcnster M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Zeidler","sequence":"additional","affiliation":[{"name":"Center for Chronic Pruritus (KCP) Department of Dermatology University Hospital M\u00fcnster M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Augustin","sequence":"additional","affiliation":[{"name":"Institute for Health Services Research in Dermatology and Nursing (IVDP) University Medical Center Hamburg\u2010Eppendorf Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulf","family":"Darsow","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergology Biederstein Faculty of Medicine Technical University of Munich Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas E.","family":"Kremer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology University Hospital Z\u00fcrich Z\u00fcrich Switzerland"},{"name":"Department of Medicine 1 Department of Gastroenterology Pneumology and Endocrinology Friedrich\u2010Alexander\u2010University Erlangen\u2010N\u00fcrnberg Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franz J.","family":"Legat","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology Medical University of Graz Graz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Koschmieder","sequence":"additional","affiliation":[{"name":"Department of Hematology Oncology Hemostaseology and Stem Cell Transplantation (Med. Clinic\u00a0IV) Faculty of Medicine RWTH Aachen University Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f6rg","family":"Kupfer","sequence":"additional","affiliation":[{"name":"Institute of Medical Psychology Justus Liebig University Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Mettang","sequence":"additional","affiliation":[{"name":"KfH Kidney Center und DKD Helios Klinik Wiesbaden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Metz","sequence":"additional","affiliation":[{"name":"Institute of Allergology Charit\u00e9, Universit\u00e4tsmedizin Berlin Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Allergology and Immunology Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Nast","sequence":"additional","affiliation":[{"name":"Division of Evidence Based Medicine (DEBM) Department of Dermatology Venereology and Allergology Charit\u00e9\u00a0\u2013 Universit\u00e4tsmedizin Berlin Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Raap","sequence":"additional","affiliation":[{"name":"University Hospital of Dermatology and Allergy Medical Center Oldenburg Oldenburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudrun","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department for Psychosomatic Medicine and Psychotherapy University Hospital M\u00fcnster M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hartmut","family":"St\u00e4nder","sequence":"additional","affiliation":[{"name":"Dermatology Bad Bentheim Office of Dermatology at Paulinenkrankenhaus Bad Bentheim and Department of Dermatology Medical Center Dortmund Dortmund Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Streit","sequence":"additional","affiliation":[{"name":"Aarau Canton Hospital Aarau Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Schut","sequence":"additional","affiliation":[{"name":"Institute of Medical Psychology Justus Liebig University Giessen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Weisshaar","sequence":"additional","affiliation":[{"name":"Devision of Occupational Dermatology Department of Dermatology University Medical Center Heidelberg Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,10,17]]},"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14830","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ddg.14830","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14830","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T13:40:40Z","timestamp":1692625240000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.14830"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10]]},"references-count":0,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1111\/ddg.14830"],"URL":"https:\/\/doi.org\/10.1111\/ddg.14830","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10]]},"assertion":[{"value":"2022-03-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}