{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T12:22:06Z","timestamp":1781094126159,"version":"3.54.1"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,1,31]],"date-time":"2023-01-31T00:00:00Z","timestamp":1675123200000},"content-version":"vor","delay-in-days":30,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>The lifetime prevalence of urticaria, a severe allergic disease, is almost 20%. It not only limits the quality of life of those affected, but also their general performance at work and in their daily activities. This publication is the first section of the Urticaria Guideline. It covers the classification and diagnosis of urticaria, taking into account the major advances in research into its causes, triggering factors and pathomechanisms. It also addresses strategies for the efficient diagnosis of the different subtypes of urticaria. This is crucial for individual, patient\u2010oriented treatment, which is covered in the second part of the guideline, published separately. This German\u2010language guideline was developed according to the criteria of the AWMF on the basis of the international English\u2010language S3 guideline with special consideration of health system characteristics in the German\u2010speaking countries.<\/jats:p><jats:p>This first part of the guideline describes the classification of urticaria, distinguishing spontaneously occurring wheals (hives) and angioedema from forms of urticaria with inducible symptoms. Urticaria is defined as sudden onset of wheals, angioedema, or both, but is to be distinguished from conditions in which wheals occur as a short\u2010term symptom, such as anaphylaxis. The diagnosis is based on (a limited number of) laboratory tests, but especially on medical history. In addition, validated instruments are available to measure the severity, activity and course of the disease.<\/jats:p>","DOI":"10.1111\/ddg.14906","type":"journal-article","created":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T07:18:52Z","timestamp":1675235932000},"page":"81-93","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["S3 Guideline Urticaria. Part 1: Classification and diagnosis of urticaria \u2013 German\u2010language adaptation of the international S3 Guideline"],"prefix":"10.1111","volume":"21","author":[{"given":"Torsten","family":"Zuberbier","sequence":"first","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Institute of Allergology  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Allergology and Immunology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Altrichter","sequence":"additional","affiliation":[{"name":"University Hospital for Dermatology und Venereology Comprehensive Allergy Center Kepler University Hospital  Linz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Bauer","sequence":"additional","affiliation":[{"name":"Urtikaria\u2010Helden e.V.  Koblenz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randolf","family":"Brehler","sequence":"additional","affiliation":[{"name":"Center for Skin Diseases University Hospital M\u00fcnster Department of Dermatology  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Knut","family":"Brockow","sequence":"additional","affiliation":[{"name":"Department und Clinic for Dermatology und Allergology am Biederstein Technical University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corinna","family":"Dressler","sequence":"additional","affiliation":[{"name":"Division of Evidence\u2010Based Medicine Department for Dermatology Venereology und Allergology Charit\u00e9 \u2010 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin Humboldt\u2010Universit\u00e4t zu Berlin and Berlin Institute of Health  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"Fluhr","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Institute of Allergology  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Allergology and Immunology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Gaskins","sequence":"additional","affiliation":[{"name":"Division of Evidence\u2010Based Medicine Department for Dermatology Venereology und Allergology Charit\u00e9 \u2010 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin Humboldt\u2010Universit\u00e4t zu Berlin and Berlin Institute of Health  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eckard","family":"Hamelmann","sequence":"additional","affiliation":[{"name":"Department for Pediatric and Adolescent Medinine Evangelisches Klinikum Bethel University Hospital OWL University of Bielefeld  Bielefeld Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"K\u00fchne","sequence":"additional","affiliation":[{"name":"Urtikaria\u2010Helden e.V.  Koblenz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Merk","sequence":"additional","affiliation":[{"name":"Department for Dermatology und Allergology University Hospital RTWH Aachen  Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert K.","family":"M\u00fclleneisen","sequence":"additional","affiliation":[{"name":"Asthma and Allergies Center  Leverkusen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Nast","sequence":"additional","affiliation":[{"name":"Division of Evidence\u2010Based Medicine Department for Dermatology Venereology und Allergology Charit\u00e9 \u2010 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin Humboldt\u2010Universit\u00e4t zu Berlin and Berlin Institute of Health  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Olze","sequence":"additional","affiliation":[{"name":"Department of Ear Nose and Throat Medicine Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin Humboldt\u2010Universit\u00e4t zu Berlin and Berlin Institute of Health  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hagen","family":"Ott","sequence":"additional","affiliation":[{"name":"Hospital for Pediatric and Adolescent Medicine Auf der Bult  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Pleimes","sequence":"additional","affiliation":[{"name":"Practice for Pediatric and Adolescent Dermatology  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"Ru\u00ebff","sequence":"additional","affiliation":[{"name":"Department and Clinic for Dermatology und Allergology LMU Hospital at the University of Munich  Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Staubach\u2010Renz","sequence":"additional","affiliation":[{"name":"Department and Clinic for Skin Diseases University Hospital at Johannes Gutenberg University Mainz  Mainz Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Wedi","sequence":"additional","affiliation":[{"name":"Hannover Medical School Dept. of Dermatology and Allergology  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus","family":"Maurer","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Institute of Allergology  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP Allergology and Immunology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,1,31]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.15090"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.04.026"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.zefq.2014.08.003"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12632"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1159\/000023902"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-198912000-00003"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2011.02570.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13621"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12348"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12991"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199506293322608"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp011186"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(99)70506-3"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2010.02496.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.19561"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vhri.2016.07.008"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-015-0134-8"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40273-016-0412-1"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2011.02580.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12900"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14203"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13209"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1997.d01-1168.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1398-9995.2003.00091.x"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12884"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2021.03.049"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13397"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2008.01726.x"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13271"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12209"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.04.050"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.12.1076"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1159\/000507218"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12739"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12547"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/ced.12107"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2014.04.007"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2016.05.026"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.13102"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2016.37.4010"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.4168\/aair.2017.9.3.212"},{"key":"e_1_2_6_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3038.2010.01120.x"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.3183"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14037"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/pai.12910"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2016-209686"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14906","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ddg.14906","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14906","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,19]],"date-time":"2023-08-19T17:51:25Z","timestamp":1692467485000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.14906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["10.1111\/ddg.14906"],"URL":"https:\/\/doi.org\/10.1111\/ddg.14906","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"2022-06-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-11","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-01-31","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}