{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T05:04:45Z","timestamp":1764997485120},"reference-count":0,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T00:00:00Z","timestamp":1669766400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Microscopically controlled surgery (MCS) comprises various methods allowing histologically proven complete resection of malignant tumors while at the same time sparing the tumor\u2010free tissue in the immediate vicinity as much as possible. All procedures subsumed under MCS have in common the marking of the excised tissue for topographical orientation, which provides an assignment of remaining tumor remnants. Indications for MCS are malignant skin tumors in problem localizations as well as aggressive subtypes of skin tumors. Established indications for MCS include basal cell carcinoma, cutaneous squamous cell carcinoma, Bowen\u2019s disease as well as Bowen\u2019s carcinoma, dermatofibrosarcoma protuberans, melanoma in chronically light\u2010damaged skin as well as acral lentiginous melanoma and Merkel cell carcinoma. For other tumors such as extramammary Paget\u2019s disease and various cutaneous sarcomas, evidence exists that MCS has demonstrated benefits, such as local recurrence rates. In addition, MCS is indicated when it is foreseeable that a complex closure technique is required and complete resection of the tumor must be assured. Various methods of MCS have been described, including 3D histology, horizontal method and Mohs surgery. A close cooperation of qualified surgeons and (dermato)pathologists as well as laboratory staff is essential for the successful application of MCS.<\/jats:p>","DOI":"10.1111\/ddg.14910","type":"journal-article","created":{"date-parts":[[2022,11,30]],"date-time":"2022-11-30T08:09:34Z","timestamp":1669795774000},"page":"1663-1674","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["S1\u2010Guideline: Microscopically controlled surgery"],"prefix":"10.1111","volume":"20","author":[{"given":"Lukas","family":"Kofler","sequence":"first","affiliation":[{"name":"Department of Dermatology and Center for Dermatologic Surgery Eberhard\u2010Karls University of T\u00fcbingen  T\u00fcbingen Germany"},{"name":"skin + more MVZ GmbH  Biberach Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjana","family":"Ziemer","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology University Hospital of Leipzig  Leipzig Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mindaugas","family":"Andrulis","sequence":"additional","affiliation":[{"name":"Institute of Pathology Ludwigshafen General Hospital Ludwigshafen am Rhein  Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominik","family":"Horn","sequence":"additional","affiliation":[{"name":"Department of Oral and Cranio\u2010Maxillofacial Surgery Saarland University Medical Center  Homburg\/Saar Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"Kulas","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Head and Neck Surgery Saarland University Medical Center  Homburg\/Saar Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Kunte","sequence":"additional","affiliation":[{"name":"Department of Dermatologic Surgery and Dermatology Artemed Fachklinik M\u00fcnchen  Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cornelia Sigrid Lissi","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Medical Supply Center for Histology Cytology and Molecular Diagnostics Trier, Wissenschaftspark Trier  Germany"},{"name":"Faculty of Medicine Saarland University Medical Center  Homburg\/Saar Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,11,30]]},"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14910","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ddg.14910","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.14910","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T16:31:28Z","timestamp":1692549088000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.14910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,30]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["10.1111\/ddg.14910"],"URL":"https:\/\/doi.org\/10.1111\/ddg.14910","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,30]]},"assertion":[{"value":"2022-11-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}