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In diesem \u00dcbersichtsartikel fassen wir die aktuellen Therapieoptionen zusammen und ber\u00fccksichtigen dabei besondere Lokalisationen (Gesicht, Capillitium, intertrigin\u00f6se\/genitale Areale, palmoplantar, N\u00e4gel) und Situationen (hyperkeratotisch, stark entz\u00fcndlich) sowie auch die Anwendung in der Schwangerschaft und Stillzeit. In der Initialphase hat sich die Kombination aus topischen Kortikosteroiden und Vitamin\u2010D\u2010Analoga als Therapie der Wahl bew\u00e4hrt sowie auch jeweils als Monotherapie. In der Erhaltungstherapie wird die Fixkombination (Bet\/Cal) 1\u20132\u00a0x pro Woche empfohlen.<\/jats:p><jats:p>Neben der richtigen Wahl der Wirkstoffe spielt auch die Wahl der richtigen Galenik eine bedeutende Rolle. Um die Adh\u00e4renz zu verbessern, ist es au\u00dferdem wichtig, die pers\u00f6nlichen Pr\u00e4ferenzen und Erfahrungen der Patienten zu ber\u00fccksichtigen. F\u00fchrt die topische Therapie nicht zu einem zufriedenstellenden Ergebnis, sollte eine zus\u00e4tzliche UV\u2010Therapie oder eine systemische Therapie allein oder in Kombination in Betracht gezogen werden.<\/jats:p>","DOI":"10.1111\/ddg.15042_g","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T15:21:01Z","timestamp":1687274461000},"page":"631-643","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lokaltherapie der Psoriasis vulgaris"],"prefix":"10.1111","volume":"21","author":[{"given":"Lejla","family":"Ramic","sequence":"first","affiliation":[{"name":"Dermatologische Abteilung Klinik Hietzing  Wien \u00d6sterreich"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Sator","sequence":"additional","affiliation":[{"name":"Dermatologische Abteilung Klinik Hietzing  Wien \u00d6sterreich"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,20]]},"reference":[{"issue":"6","key":"e_1_2_7_2_1","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1111\/ddg.14508","article-title":"German S3\u2010Guideline on the treatment of Psoriasis vulgaris, adapted from EuroGuiDerm \u2013 Part 1: Treatment goals and treatment recommendations","volume":"19","author":"Nast A","year":"2021","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.4006"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61909-7"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-010-1080-1"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-016-1651-x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2012.04525.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2014.2294"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2008.01.015"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-4362.1999.00500.x"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1975.01630180068008"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2006.21.1.95"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.08113.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.10.016"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22168749"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S39082"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-016-0607-9"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015550252948194"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2003.130"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/120347540300700301"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12461062"},{"key":"e_1_2_7_22_1","volume-title":"Topische Therapie der Psoriasis.1. 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