{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:49Z","timestamp":1787014069683,"version":"build-2736575974"},"reference-count":174,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T00:00:00Z","timestamp":1694476800000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2023,9]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    The consensus\u2010based guideline \u201cDiagnosis, prevention, and treatment of hand eczema (HE)\u201d provides concrete instructions and recommendations for diagnosis, prevention, and therapy of HE based on an evidence\u2010 and consensus\u2010based approach. The guideline was created based on the German guideline \u201c\n                    <jats:italic>Management von Handekzemen<\/jats:italic>\n                    \u201d from 2009 and the current guideline of the European Society of Contact Dermatitis (ESCD) \u201cGuidelines for diagnosis, prevention, and treatment of hand eczema\u201d from 2022. The general goal of the guideline is to provide dermatologists and allergologists in practice and clinics with an accepted, evidence\u2010based decision\u2010making tool for selecting and conducting suitable and sufficient therapy for patients with hand eczema. The guideline is based on two Cochrane reviews of therapeutic and preventive interventions for HE. The remaining chapters were mainly developed and consented based on non\u2010systematic literature research by the expert group. The expert group consisted of members of allergological and occupational dermatological professional associations and working groups, a patient representative, and methodologists. The proposals for recommendations and key statements were consented by using a nominal group process during a consensus conference on September 15, 2022. The structured consensus\u2010building process was professionally moderated. This guideline is valid until February 22, 2028.\n                  <\/jats:p>","DOI":"10.1111\/ddg.15179","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T00:00:40Z","timestamp":1694563240000},"page":"1054-1074","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["S2k guideline diagnosis, prevention, and therapy of hand eczema"],"prefix":"10.1111","volume":"21","author":[{"given":"Andrea","family":"Bauer","sequence":"first","affiliation":[{"name":"Department of Dermatology University Hospital Carl Gustav Carus Technical University Dresden  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Brans","sequence":"additional","affiliation":[{"name":"Department of Dermatology Environmental Medicine and Health Theory University of Osnabr\u00fcck Osnabr\u00fcck Germany and Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) at the University of Osnabr\u00fcck  Osnabr\u00fcck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randolf","family":"Brehler","sequence":"additional","affiliation":[{"name":"Department of Allergy Occupational Dermatology and Environmental Medicine University Hospital M\u00fcnster  M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"B\u00fcttner","sequence":"additional","affiliation":[{"name":"Privat practice for dermatology  Dieburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinrich","family":"Dickel","sequence":"additional","affiliation":[{"name":"Bochum Department of Dermatology Venereology and Allergology St. Josef Hospital University Medical Center Ruhr University Bochum  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Elsner","sequence":"additional","affiliation":[{"name":"Privat practice for dermatology and allergology SRH Hospital Gera  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manig\u00e9","family":"Fartasch","sequence":"additional","affiliation":[{"name":"Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA), Institute of the Ruhr University Bochum  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Herzog","sequence":"additional","affiliation":[{"name":"University Cancer Center University Hospital Carl Gustav Carus Technical University Dresden  Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swen\u2010Malte","family":"John","sequence":"additional","affiliation":[{"name":"Department of Dermatology Environmental Medicine and Health Theory University of Osnabr\u00fcck, Osnabr\u00fcck, Germany and Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) at the University of Osnabr\u00fcck  Osnabr\u00fcck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arno","family":"K\u00f6llner","sequence":"additional","affiliation":[{"name":"Dermatology Group Practice  Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia\u2010Tatjana","family":"Maul","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans","family":"Merk","sequence":"additional","affiliation":[{"name":"Professor of Dermatology and Allergology Former Chairman of the Department of Dermatology RWTH University  Aachen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonja","family":"Molin","sequence":"additional","affiliation":[{"name":"Division of Dermatology Department of Medicine Queen's University  Kingston Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Nast","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Division of Evidence\u2010Based Medicine (dEBM) Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin corporate member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios D.","family":"Nikolakis","sequence":"additional","affiliation":[{"name":"Departments of Dermatology Venereology Allergology and Immunology Staedtisches Klinikum Dessau Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg  Dessau Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sybille","family":"Schliemann","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Jena  Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph","family":"Skudlik","sequence":"additional","affiliation":[{"name":"Department of Dermatology Environmental Medicine and Health Theory University of Osnabr\u00fcck, Osnabr\u00fcck, Germany and Institute for Interdisciplinary Dermatologic Prevention and Rehabilitation (iDerm) at the University of Osnabr\u00fcck  Osnabr\u00fcck Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Weisshaar","sequence":"additional","affiliation":[{"name":"Occupational Dermatology Department of Dermatology University Hospital Heidelberg  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Werfel","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Hannover Medical School  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Zidane","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Division of Evidence\u2010Based Medicine (dEBM) Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin corporate member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margitta","family":"Worm","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,9,12]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14035"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0379.2009.07061.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.12510_1"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08907.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13308"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16061"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01915.x"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2010.04001.x"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2009.01669.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2000.03361.x"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700750"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0022-202X.2005.23723.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13502"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.14476"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12134"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.3876"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1980.tb05572.x"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00420-002-0418-1"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.17870"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12674"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.13169"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13041"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12971"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12429"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.13777"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2011.10394.x"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13479"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14319"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1104084"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-019-04474-5"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01911.x"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13572"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12945"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13824"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16083"},{"key":"e_1_2_5_37_1","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1111\/ddg.13971","article-title":"S3 guidelines: Epicutaneous patch testing with contact allergens and drugs \u2013 Short version, Part 2","volume":"17","author":"Mahler V","year":"2019","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_5_38_1","first-page":"79","article-title":"[Criteria of atopic skin diathesis]","volume":"39","author":"Diepgen TL","year":"1991","journal-title":"Dermatol Beruf Umwelt"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(96)00119-9"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02827.x"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12846"},{"key":"e_1_2_5_42_1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/ddg.12922","article-title":"Hand dermatitis \u2013 differential diagnoses, diagnostics, and treatment options","volume":"14","author":"Mahler V","year":"2016","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_5_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14016"},{"key":"e_1_2_5_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-015-0130-z"},{"key":"e_1_2_5_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12432"},{"key":"e_1_2_5_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1985.tb02528.x"},{"key":"e_1_2_5_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.13956"},{"key":"e_1_2_5_48_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1007\/s15007-019-1949-z","article-title":"Epikutantestung mit patienteneigenem Material und Arbeitsstoffen","volume":"28","author":"Geier J","year":"2019","journal-title":"Allergo J"},{"key":"e_1_2_5_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1986.tb01229.x"},{"key":"e_1_2_5_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1998.tb05850.x"},{"key":"e_1_2_5_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2010.01710.x"},{"key":"e_1_2_5_52_1","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/j.1610-0387.2011.07671.x","article-title":"New\u201d techniques for more sensitive patch testing?","volume":"9","author":"Dickel H","year":"2011","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_5_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12758"},{"key":"e_1_2_5_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-019-04528-8"},{"key":"e_1_2_5_55_1","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1111\/ddg.13683_g","article-title":"Empfehlungen der Arbeitsgruppe \u201cPhotopatchtest\u201d der Deutschen Kontaktallergie\u2010Gruppe (DKG) zur Durchf\u00fchrung des Photopatchtests","volume":"16","author":"Geier J","year":"2018","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_5_56_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2003.00126.x"},{"key":"e_1_2_5_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-021-04810-8"},{"key":"e_1_2_5_58_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0000000000000621"},{"key":"e_1_2_5_59_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2015.2593"},{"key":"e_1_2_5_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-018-4174-x"},{"key":"e_1_2_5_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1976.tb02975.x"},{"key":"e_1_2_5_62_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12653"},{"key":"e_1_2_5_63_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13547"},{"key":"e_1_2_5_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03370726"},{"key":"e_1_2_5_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2011.02728.x"},{"key":"e_1_2_5_66_1","doi-asserted-by":"publisher","DOI":"10.1186\/2045-7022-3-3"},{"key":"e_1_2_5_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.waojou.2019.100080"},{"key":"e_1_2_5_68_1","first-page":"177","article-title":"Leitlinien\u2010Update 061\/017 In\u2010vitro\u2010Allergiediagnostik1, 2 \/In\u2010vitro allergy diagnostics Deutsche Gesellschaft f\u00fcr Allergologie und Klinische Immunologie (DGAKI), \u00c4rzteverband deutscher Allergologen (\u00c4DA), Gesellschaft f\u00fcr p\u00e4diatrische Allergologie (GPA), Deutsche Dermatologische Gesellschaft (DDG)","volume":"34","author":"Renz H","year":"2010","journal-title":"Lab Medizin"},{"key":"e_1_2_5_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09353.x"},{"key":"e_1_2_5_70_1","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1111\/ddg.12980","article-title":"Are the classic diagnostic methods in mycology still state of the art?","volume":"14","author":"Wiegand C","year":"2016","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_5_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.06.027"},{"key":"e_1_2_5_72_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3008946"},{"key":"e_1_2_5_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/exd.13077"},{"key":"e_1_2_5_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14015"},{"key":"e_1_2_5_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2022.12.024"},{"key":"e_1_2_5_76_1","doi-asserted-by":"publisher","DOI":"10.5414\/DBP54108"},{"key":"e_1_2_5_77_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12102"},{"key":"e_1_2_5_78_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2012.07890_suppl.x"},{"key":"e_1_2_5_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-019-4463-z"},{"key":"e_1_2_5_80_1","unstructured":"Berufsgenossenschaft f\u00fcr Gesundheitsdienst undWohlfahrtspflege.Technische Regeln f\u00fcr Gefahrstoffe: Gef\u00e4hrdung durch Hautkontakt \u2013 Ermittlung Beurteilung Ma\u00dfnahmen (TGRS 401) \u2013 Fassung v. 18.11.2022. 23.02.2023 Available from:https:\/\/www.bgw\u2010online.de\/bgw\u2010online\u2010de\/service\/medien\u2010arbeitshilfen\/medien\u2010center\/gefaehrdung\u2010durch\u2010hautkontakt\u2010ermittlung\u2010beurteilung\u201013784[Last Accessed February 23 2023]."},{"key":"e_1_2_5_81_1","doi-asserted-by":"publisher","DOI":"10.5414\/DBX00330"},{"key":"e_1_2_5_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13181"},{"key":"e_1_2_5_83_1","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2011-100220"},{"key":"e_1_2_5_84_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12846"},{"key":"e_1_2_5_85_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12113"},{"key":"e_1_2_5_86_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.15875"},{"key":"e_1_2_5_87_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12934"},{"key":"e_1_2_5_88_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2001.440509.x"},{"key":"e_1_2_5_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1999.tb06162.x"},{"key":"e_1_2_5_90_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2002.470501.x"},{"key":"e_1_2_5_91_1","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2014-102708"},{"key":"e_1_2_5_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.05.037"},{"key":"e_1_2_5_93_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13561"},{"key":"e_1_2_5_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1996.tb02102.x"},{"key":"e_1_2_5_95_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12470"},{"key":"e_1_2_5_96_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1989.tb01425.x"},{"key":"e_1_2_5_97_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15813"},{"key":"e_1_2_5_98_1","doi-asserted-by":"publisher","DOI":"10.2486\/indhealth.45.645"},{"key":"e_1_2_5_99_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1996.tb02196.x"},{"key":"e_1_2_5_100_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12131"},{"key":"e_1_2_5_101_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.1995.tb00751.x"},{"key":"e_1_2_5_102_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.14316"},{"key":"e_1_2_5_103_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2007.07944.x"},{"key":"e_1_2_5_104_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0105-1873.2006.00890.x"},{"key":"e_1_2_5_105_1","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/ddg.12617","article-title":"S1 guideline on occupational skin products: protective creams, skin cleansers, skin care products (ICD 10: L23, L24) \u2013 short version","volume":"13","author":"Fartasch M","year":"2015","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_5_106_1","article-title":"Interventions for preventing occupational irritant hand dermatitis","volume":"4","author":"Bauer A","year":"2018","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_5_107_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1997.03890430077010"},{"key":"e_1_2_5_108_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.09643.x"},{"key":"e_1_2_5_109_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.12104"},{"key":"e_1_2_5_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13550"},{"key":"e_1_2_5_111_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12750"},{"key":"e_1_2_5_112_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-018-8705-0"},{"key":"e_1_2_5_113_1","doi-asserted-by":"publisher","DOI":"10.5414\/DBP53172"},{"key":"e_1_2_5_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2009.11.033"},{"key":"e_1_2_5_115_1","article-title":"Interventions for hand eczema","volume":"4","author":"Christoffers WA","year":"2019","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_5_116_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06305.x"},{"key":"e_1_2_5_117_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18295"},{"key":"e_1_2_5_118_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13828"},{"key":"e_1_2_5_119_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2004.06270.x"},{"key":"e_1_2_5_120_1","unstructured":"ClinicalTrials.gov. Identifier NCT00556855. A 4\u2010week randomized double\u2010blind placebocontrolled right\u2010left comparison study with E\u2010DO\u00ae in chronic hand dermatitis [Comparison study with E\u2010DO in chronic hand dermatitis] [Internet].2020Sep 18 Available from:https:\/\/clinicaltrials.gov\/ct2\/show\/NCT00556855[Last accessed September 18 2020]."},{"key":"e_1_2_5_121_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2003.00119.x"},{"key":"e_1_2_5_122_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0536.2000.042002077.x"},{"key":"e_1_2_5_123_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0964"},{"key":"e_1_2_5_124_1","doi-asserted-by":"publisher","DOI":"10.1067\/mic.2000.107425"},{"key":"e_1_2_5_125_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-015-0146-4"},{"key":"e_1_2_5_126_1","article-title":"Emollients and moisturisers for eczema","volume":"2","author":"Zuuren EJ","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_5_127_1","first-page":"328","article-title":"A randomized, double\u2010blind phase 4 study of the efficacy and safety of ethanol\u2010free clobetasol propionate foam, 0.05%, vs vehicle foam in the treatment of chronic hand dermatitis","volume":"12","author":"Kircik LH","year":"2013","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_5_128_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1999.02819.x"},{"key":"e_1_2_5_129_1","first-page":"20","article-title":"Topical corticosteroid application and the structural and functional integrity of the epidermal barrier","volume":"6","author":"Del Rosso JQ","year":"2013","journal-title":"J Clin Aesthet Dermatol"},{"key":"e_1_2_5_130_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12053.x"},{"key":"e_1_2_5_131_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0906-6705.2006.00435.x"},{"key":"e_1_2_5_132_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0353.2004.03626.x"},{"key":"e_1_2_5_133_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajd.12762"},{"key":"e_1_2_5_134_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2011.04128.x"},{"key":"e_1_2_5_135_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2005.06410.x"},{"key":"e_1_2_5_136_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta4370"},{"key":"e_1_2_5_137_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.1998.02498.x"},{"key":"e_1_2_5_138_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.15071"},{"key":"e_1_2_5_139_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.117856"},{"key":"e_1_2_5_140_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0536.2011.01967.x"},{"key":"e_1_2_5_141_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2017.2437"},{"key":"e_1_2_5_142_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3220"},{"key":"e_1_2_5_143_1","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2006.27.2915"},{"key":"e_1_2_5_144_1","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1111\/ddg.13579_g","article-title":"Aktualisierung der S1\u2010Leitlinie zur Definition und Therapie der prim\u00e4ren Hyperhidrose","volume":"16","author":"Rzany B","year":"2018","journal-title":"J Dtsch Dermatol Ges"},{"key":"e_1_2_5_145_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16238"},{"key":"e_1_2_5_146_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0781.2009.00419.x"},{"key":"e_1_2_5_147_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.12.1463"},{"key":"e_1_2_5_148_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-966365"},{"key":"e_1_2_5_149_1","article-title":"A comparative study of UVA\u20101 phototherapy versus betamethasone valerate 0.1% cream for chronic vesicular Handekzem","volume":"64","author":"Said N","journal-title":"J Am Acad Dermatol"},{"key":"e_1_2_5_150_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12350.x"},{"key":"e_1_2_5_151_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1987.tb04093.x"},{"key":"e_1_2_5_152_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1985.tb04862.x"},{"key":"e_1_2_5_153_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1984.tb06607.x"},{"key":"e_1_2_5_154_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1984.tb06608.x"},{"key":"e_1_2_5_155_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1987.tb04094.x"},{"key":"e_1_2_5_156_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1989.tb01401.x"},{"key":"e_1_2_5_157_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2008.08487.x"},{"key":"e_1_2_5_158_1","unstructured":"European Medicines Agency.SmPC text alitretinoin.2020Sep 24. Available from:https:\/\/www.medicines.org.uk\/emc\/product\/10466\/smpc[Last accessed September 24 2020]."},{"key":"e_1_2_5_159_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09572.x"},{"key":"e_1_2_5_160_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2012.04396.x"},{"key":"e_1_2_5_161_1","doi-asserted-by":"publisher","DOI":"10.1080\/000155501317140089"},{"key":"e_1_2_5_162_1","doi-asserted-by":"publisher","DOI":"10.2340\/0001555576371376"},{"key":"e_1_2_5_163_1","doi-asserted-by":"publisher","DOI":"10.1080\/00015559850135814"},{"key":"e_1_2_5_164_1","article-title":"Efficacy and safety of treatment with oral alitretinoin and oral cyclosporine for chronic hand eczema: a retrospective review of 118 cases","volume":"100","author":"Jang YJ","year":"2020","journal-title":"Acta Derm Venereol"},{"key":"e_1_2_5_165_1","doi-asserted-by":"publisher","DOI":"10.4103\/0378-6323.104679"},{"key":"e_1_2_5_166_1","first-page":"1389","article-title":"Methotrexate versus acitretin in the treatment of chronic hand dermatitis","volume":"14","author":"O'Shea PM","year":"2015","journal-title":"J Drugs Dermatol"},{"key":"e_1_2_5_167_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13253"},{"key":"e_1_2_5_168_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.14104"},{"key":"e_1_2_5_169_1","doi-asserted-by":"publisher","DOI":"10.1111\/1346-8138.14982"},{"key":"e_1_2_5_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2019.12.053"},{"key":"e_1_2_5_171_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13501"},{"key":"e_1_2_5_172_1","doi-asserted-by":"publisher","DOI":"10.1111\/cod.13693"},{"key":"e_1_2_5_173_1","unstructured":"WerfelT et\u00a0al.S2k\u2010Leitlinie Neurodermitis (AWMF\u2010Registernummer 013\u2013027). Available from:https:\/\/register.awmf.org\/de\/leitlinien\/detail\/013\u2010027[Last accessed February 23 2023]."},{"key":"e_1_2_5_174_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.18469"},{"key":"e_1_2_5_175_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.21037"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.15179","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T23:03:19Z","timestamp":1703718199000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.15179"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":174,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1111\/ddg.15179"],"URL":"https:\/\/doi.org\/10.1111\/ddg.15179","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"2023-05-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}