{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T20:40:12Z","timestamp":1773088812626,"version":"3.50.1"},"reference-count":43,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T00:00:00Z","timestamp":1698105600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Folliculitis decalvans (FD) is a type of primary neutrophilic cicatricial alopecia often leading to irreversible hair loss. Data on its epidemiology, clinical features, outcomes, and prognostic factors are limited.<\/jats:p><\/jats:sec><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate a cohort of patients with FD and identify characteristics of severe disease and prognostic factors which impede remission.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>This retrospective cohort study included 192 patients diagnosed with FD and followed for at least six months at a tertiary center between 2010 and 2020.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a diagnostic\u00a0delay averaging 22.2 (\u00b1\u00a029.7) months. Comorbid follicular occlusion disorders were common. Bacterial cultures were positive in 45.6% of the cases, with <jats:italic>Staphylococcus (S.) aureus<\/jats:italic> being the most common pathogen. Severe disease was associated with comorbid hidradenitis suppurativa and a positive bacterial culture, particularly <jats:italic>S.\u00a0aureus<\/jats:italic>. 50.7% of patients experienced complete remission: 32% within the first six months of treatment and 18.7% later during follow\u2010up. Relapses were frequent. Negative prognostic factors for achieving remission included younger age and a positive bacterial culture.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There is a need for the education of dermatologists to reduce the diagnostic delay. Screening FD patients for comorbid hidradenitis suppurativa and obtaining bacterial cultures is important for treatment planning.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ddg.15202","type":"journal-article","created":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T03:14:11Z","timestamp":1698203651000},"page":"1469-1477","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Diagnostic delay, comorbid hidradenitis suppurativa and the prognostic value of bacterial culture in folliculitis decalvans: A cohort study"],"prefix":"10.1111","volume":"21","author":[{"given":"Anna","family":"Lyakhovitsky","sequence":"first","affiliation":[{"name":"Department of Dermatology Sheba Medical Center Tel\u2010Hashomer  Ramat\u2010Gan Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oz","family":"Segal","sequence":"additional","affiliation":[{"name":"Department of Dermatology Sheba Medical Center Tel\u2010Hashomer  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