{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:56:48Z","timestamp":1747184208308,"version":"3.40.5"},"reference-count":43,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,12,11]],"date-time":"2023-12-11T00:00:00Z","timestamp":1702252800000},"content-version":"vor","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Zusammenfassung<\/jats:title><jats:sec><jats:title>Hintergrund<\/jats:title><jats:p>Folliculitis decalvans (FD) ist eine prim\u00e4re neutrophile vernarbende Alopezie, die h\u00e4ufig zu irreversiblem Haarverlust f\u00fchrt. Daten zu Epidemiologie, klinischen Merkmalen, Folgen und prognostischen Faktoren sind nur eingeschr\u00e4nkt verf\u00fcgbar.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ziel<\/jats:title><jats:p>Die Beurteilung einer Patientenkohorte mit FD sowie die Charakterisierung schwerer Krankheitsverl\u00e4ufe und prognostischer Faktoren, die eine Remission verhindern.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patienten und Methoden<\/jats:title><jats:p>Diese retrospektive Kohortenstudie umfasste 192\u00a0Patienten, bei denen zwischen 2010 und 2020 an einem terti\u00e4ren Zentrum eine FD diagnostiziert und die mindestens sechs Monate nachverfolgt wurden.<\/jats:p><\/jats:sec><jats:sec><jats:title>Ergebnisse<\/jats:title><jats:p>Die Diagnose wurde im Mittel um 22,2 (\u00b1\u00a029,7) Monate verz\u00f6gert gestellt. Komorbide Erkrankungen mit Okklusion der Haarfollikel waren h\u00e4ufig. In 45,6% der F\u00e4lle waren Bakterienkulturen positiv, am h\u00e4ufigsten mit <jats:italic>Staphylococcus (S.)<\/jats:italic>\u00a0<jats:italic>aureus<\/jats:italic>. Schwere Krankheitsverl\u00e4ufe waren mit komorbider Hidradenitis suppurativa und positiver Bakterienkultur, insbesondere <jats:italic>S.\u00a0aureus<\/jats:italic>, assoziiert. Bei 50,7% der Patienten kam es zu vollst\u00e4ndiger Remission: Bei 32% innerhalb der ersten sechs Monate der Behandlung und bei 18,7% w\u00e4hrend der Nachkontrolle. Rezidive waren h\u00e4ufig. Negative Prognosefaktoren bez\u00fcglich der Remission waren j\u00fcngeres Alter und positive Bakterienkultur.<\/jats:p><\/jats:sec><jats:sec><jats:title>Schlussfolgerungen<\/jats:title><jats:p>Es besteht Bedarf hinsichtlich der Ausbildung von Dermatologen, um die Diagnoseverz\u00f6gerung zu reduzieren. Das Screening von FD\u2010Patienten auf komorbide Hidradenitis suppurativa und Bakterienkulturen sind wichtig f\u00fcr die Behandlungsplanung.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ddg.15202_g","type":"journal-article","created":{"date-parts":[[2023,12,12]],"date-time":"2023-12-12T20:09:51Z","timestamp":1702411791000},"page":"1469-1478","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnoseverz\u00f6gerung, komorbide Hidradenitis suppurativa und die prognostische Bedeutung bakterieller Kulturen bei Folliculitis decalvans: eine Kohortenstudie"],"prefix":"10.1111","volume":"21","author":[{"given":"Anna","family":"Lyakhovitsky","sequence":"first","affiliation":[{"name":"Department of Dermatology Sheba Medical Center Tel\u2010Hashomer  Ramat\u2010Gan Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oz","family":"Segal","sequence":"additional","affiliation":[{"name":"Department of Dermatology 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