{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:41:13Z","timestamp":1787503273100,"version":"build-2736575974"},"reference-count":2,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:00:00Z","timestamp":1697414400000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Actinic keratosis (AK) are common lesions in light\u2010skinned individuals that can potentially progress to cutaneous squamous cell carcinoma (cSCC). Both conditions may be associated with significant morbidity and constitute a major disease burden, especially among the elderly. To establish an evidence\u2010based framework for clinical decision making, the guideline \u201cactinic keratosis and cutaneous squamous cell carcinoma\u201d was updated and expanded by the topics cutaneous squamous cell carcinoma\n                    <jats:italic>in situ<\/jats:italic>\n                    (Bowen's disease) and actinic cheilitis. The guideline is aimed at dermatologists, general practitioners, ear nose and throat specialists, surgeons, oncologists, radiologists and radiation oncologists in hospitals and office\u2010based settings, as well as other medical specialties, policy makers and insurance funds involved in the diagnosis and treatment of patients with AK and cSCC. A separate guideline exists for patients and their relatives. In this part, we will address aspects relating to AK, actinic cheilitis, Bowen's disease, occupational disease and care structures.\n                  <\/jats:p>","DOI":"10.1111\/ddg.15231","type":"journal-article","created":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T21:36:55Z","timestamp":1697492215000},"page":"1249-1262","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["S3 guideline \u201eactinic keratosis and cutaneous squamous cell carcinoma\u201c\u2013 update 2023, part 1: treatment of actinic keratosis, actinic cheilitis, cutaneous squamous cell carcinoma in situ (Bowen's disease), occupational disease and structures of care"],"prefix":"10.1111","volume":"21","author":[{"given":"Markus V.","family":"Heppt","sequence":"first","affiliation":[{"name":"Department of Dermatology Uniklinikum Erlangen Friedrich\u2010Alexander\u2010Universit\u00e4t Erlangen\u2010N\u00fcrnberg (FAU)  Erlangen Germany"},{"name":"Comprehensive Cancer Center Erlangen\u2010European Metropolitan Area of Nuernberg (CCC ER\u2010EMN)  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Leiter","sequence":"additional","affiliation":[{"name":"Center of Dermatooncology University Department of Dermatooncology Eberhard\u2010Karls\u2010University Tuebingen  T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Steeb","sequence":"additional","affiliation":[{"name":"Department of Dermatology Uniklinikum Erlangen Friedrich\u2010Alexander\u2010Universit\u00e4t Erlangen\u2010N\u00fcrnberg (FAU)  Erlangen Germany"},{"name":"Comprehensive Cancer Center Erlangen\u2010European Metropolitan Area of Nuernberg (CCC ER\u2010EMN)  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mareike","family":"Alter","sequence":"additional","affiliation":[{"name":"Department of Dermatology Johannes Wesling Medical Center Ruhr University Bochum Campus Minden  Minden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Amaral","sequence":"additional","affiliation":[{"name":"Center of Dermatooncology University Department of Dermatooncology Eberhard\u2010Karls\u2010University Tuebingen  T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Bauer","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Hospital Carl Gustav Carus, Technical University Dresden  Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Falk G.","family":"Bechara","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venerology and Allergology St. Josef\u2010Hospital Ruhr\u2010University Bochum  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen C.","family":"Becker","sequence":"additional","affiliation":[{"name":"Translational Skin Cancer Research (TSCR) DKTK Essen\/D\u00fcsseldorf University Medicine Essen  Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eckhard W.","family":"Breitbart","sequence":"additional","affiliation":[{"name":"Association of Dermatological Prevention  Buxtehude Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helmut","family":"Breuninger","sequence":"additional","affiliation":[{"name":"Center of Dermatooncology University Department of Dermatooncology Eberhard\u2010Karls\u2010University Tuebingen  T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Diepgen","sequence":"additional","affiliation":[{"name":"Institute of Clinical Social Medicine University Heidelberg  Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Dirschka","sequence":"additional","affiliation":[{"name":"CentroDerm Wuppertal  Wuppertal Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Eigentler","sequence":"additional","affiliation":[{"name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin corporate member of Freie Universit\u00e4t Berlin and Humboldt Universit\u00e4t zu Berlin  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. K. Stephan","family":"El Gammal","sequence":"additional","affiliation":[{"name":"Clinic of Dermatology Hospital Bethesda  Freudenberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moritz","family":"Felcht","sequence":"additional","affiliation":[{"name":"Department of Dermatosurgery St. Josefhospital Heidelberg GmbH  Heidelberg Germany"},{"name":"Department of Dermatology Venereology und Allergy University Medicine Mannheim  Mannheim Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Flaig","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital, LMU Munich  M\u00fcnchen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Follmann","sequence":"additional","affiliation":[{"name":"German Guideline Program in Oncology German Cancer Society  Berlin 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Clinics Stade Buxtehude GmbH Medical Center Buxtehude  Buxtehude Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doroth\u00e9e","family":"Nashan","sequence":"additional","affiliation":[{"name":"Department of Dermatology Klinikum Dortmund  Dortmund Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Nothacker","sequence":"additional","affiliation":[{"name":"Association of the Scientific Medical Societies in Germany (AWMF) Institute for Medical Knowledge Management, c\/o Philipps Universit\u00e4t Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Pfannenberg","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology Eberhard\u2010Karls\u2010University Tuebingen  T\u00fcbingen 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Eberhard\u2010Karls\u2010University Tuebingen  T\u00fcbingen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carola","family":"Berking","sequence":"additional","affiliation":[{"name":"Department of Dermatology Uniklinikum Erlangen Friedrich\u2010Alexander\u2010Universit\u00e4t Erlangen\u2010N\u00fcrnberg (FAU)  Erlangen Germany"},{"name":"Comprehensive Cancer Center Erlangen\u2010European Metropolitan Area of Nuernberg (CCC ER\u2010EMN)  Erlangen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"issue":"3","key":"e_1_2_9_2_1","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/ddg.14048","article-title":"S3 guideline for actinic keratosis and cutaneous squamous cell carcinoma \u2010 short version, part 1: diagnosis, interventions for actinic keratoses, care structures and quality\u2010of\u2010care indicators","volume":"18","author":"Heppt MV","year":"2020","journal-title":"J Dtsch Dermatol Ges"},{"issue":"4","key":"e_1_2_9_3_1","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1111\/ddg.14072","article-title":"S3 guideline for actinic keratosis and cutaneous squamous cell carcinoma (cSCC) \u2010 short version, part 2: epidemiology, surgical and systemic treatment of cSCC, follow\u2010up, prevention and occupational disease","volume":"18","author":"Leiter U","year":"2020","journal-title":"J Dtsch Dermatol Ges"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.15231","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T21:40:14Z","timestamp":1697492414000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.15231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":2,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1111\/ddg.15231"],"URL":"https:\/\/doi.org\/10.1111\/ddg.15231","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"2023-03-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-07-27","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}