{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T07:33:10Z","timestamp":1788939190645,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,2,2]],"date-time":"2024-02-02T00:00:00Z","timestamp":1706832000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Summary<\/jats:title><jats:sec><jats:title>Background and Objectives<\/jats:title><jats:p>Serovar L1\u2013L3 of <jats:italic>Chlamydia trachomatis<\/jats:italic> (CT) causes lymphogranuloma venereum (LGV). A surge in LGV\u2010cases has been observed among HIV\u2010positive men who have sex with men (MSM). Discrimination between LGV and non\u2010LGV is pivotal since it has major treatment implications. Here, we aimed to determine the prevalence and characteristics of LGV among CT\u2010infections.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and Methods<\/jats:title><jats:p>All CT\u2010positive results from 04\/2014\u201312\/2021 at the four largest Austrian HIV and STI clinics were evaluated. Disease characteristics and patient demographics were analyzed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, n\u00a0 = \u00a02,083 infections of CT were documented in n\u00a0 = \u00a01,479 individual patients: median age was 31.4\u00a0years, 81% were male, 59% MSM, 44% HIV\u2010positive, 13% on HIV pre\u2010exposure\u2010prophylaxis. Available serovar analyses (61% [1,258\/2,083]) showed L1\u2013L3 in 15% (192\/1,258). Considering only MSM with rectal CT\u2010infection, LGV accounted for 23% (101\/439). Cases of LGV vs. other CT\u2010infections were primarily MSM (92% [177\/192] vs. 62% [1,179\/1,891], p\u00a0&lt;\u00a00.001), more often HIV\u2010positive (64% [116\/180] vs. 46% [631\/1,376]; p\u00a0&lt;\u00a00.001) and had frequently concomitant syphilis infection (18% [32\/180] vs. 7% [52\/749]; p\u00a0&lt;\u00a00.001). LGV commonly manifested as proctitis (38% [72\/192]) whereas 45% (87\/192) were asymptomatic.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Lymphogranuloma venereum accounted for 23% of rectal CT\u2010infections in MSM. Furthermore, 45% of all LGV\u2010cases were asymptomatic. In the absence of CT\u2010serovar analysis, a high LGV prevalence should be considered in risk\u2010populations and guide empiric treatment selection.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ddg.15329","type":"journal-article","created":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T04:24:37Z","timestamp":1706934277000},"page":"389-397","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Asymptomatic lymphogranuloma venereum is commonly found among men who have sex with men in Austria"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1807-8258","authenticated-orcid":false,"given":"David","family":"Chromy","sequence":"first","affiliation":[{"name":"Department of Dermatology Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birgit","family":"Sadoghi","sequence":"additional","affiliation":[{"name":"Department of Dermatology 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