{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:47:48Z","timestamp":1787014068749,"version":"build-2736575974"},"reference-count":18,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2024,6,23]],"date-time":"2024-06-23T00:00:00Z","timestamp":1719100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Follow\u2010up protocols in patients after complete resection of high\u2010risk cutaneous tumors lead to a discovery of metastases in very early stages, but surgery on non\u2010palpable lesions proves to be challenging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>In this monocenter retrospective study 39 patients suffering from malignant skin tumors with suspicious non\u2010palpable lesions located in the lymph nodes (90%) or deep subcutaneously\/intramuscularly (10%) were included. In 21 patients the lesions were excised under ultrasound guidance, and 18 patients received a wire marking before surgery. Both patient groups were compared regarding successful intraoperative finding of the lesion, duration of the procedure, and complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Wire marking led to a significantly higher intraoperative detection rate of 100% versus 76% (p\u00a0&lt;\u00a00.05). The average time needed for the complete procedure (p = 0.91) or the rate of complications (p = 0.70) did not differ significantly between both groups. The size of the malignant lesions successfully removed by wire marking was significantly smaller (p\u00a0&lt;\u00a00.05). Of all 34 detected lesions only 20 (58.8%) were confirmed to be malignant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Wire marking increases the detection rate of non\u2010palpable suspicious subcutaneous or lymphatic lesions. It leads to earlier diagnosis of metastasis but also allows to avoid unnecessary complete lymph node dissection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ddg.15434","type":"journal-article","created":{"date-parts":[[2024,6,24]],"date-time":"2024-06-24T01:19:27Z","timestamp":1719191967000},"page":"1089-1095","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Higher intraoperative detection rate of suspicious non\u2010palpable lesions using wire marking in skin cancer patients"],"prefix":"10.1111","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3351-8266","authenticated-orcid":false,"given":"Julia K.","family":"Tietze","sequence":"first","affiliation":[{"name":"Clinic and Policlinic for Dermatology and Venereology University Medical Center Rostock, (Ringgold ID: RIN39071)  Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4281-6863","authenticated-orcid":false,"given":"Steffen","family":"Emmert","sequence":"additional","affiliation":[{"name":"Clinic and Policlinic for Dermatology and Venereology University Medical Center Rostock, (Ringgold ID: RIN39071)  Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulina","family":"Troitzsch","sequence":"additional","affiliation":[{"name":"Clinic and Policlinic for Dermatology and Venereology University Medical Center Rostock, (Ringgold ID: RIN39071)  Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susen","family":"Rode","sequence":"additional","affiliation":[{"name":"Clinic and Policlinic for Dermatology and Venereology University Medical Center Rostock, (Ringgold ID: RIN39071)  Rostock Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2014.08.036"},{"issue":"21","key":"e_1_2_7_3_1","first-page":"591","article-title":"Vital signs: melanoma incidence and mortality trends and projections \u2013 United States, 1982\u20132030","volume":"64","author":"Guy GP","year":"2015","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2019.0440"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-023-13306-9"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0129476"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2021.07.002"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02807237"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13244-019-0803-x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.4103\/JCAS.JCAS_192_19"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.20170740"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.157.4.1892023"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/tsaco-2017-000113"},{"issue":"27","key":"e_1_2_7_14_1","first-page":"469","article-title":"Is anesthesia dangerous?","volume":"108","author":"Gottschalk A","year":"2011","journal-title":"Dtsch Arztebl Int"},{"issue":"9","key":"e_1_2_7_15_1","first-page":"1","article-title":"Management strategies for the treatment and prevention of postoperative\/postdischarge nausea and vomiting: an updated review","volume":"983","author":"Elvir\u2010Lazo OL","year":"2020","journal-title":"F1000Res"},{"key":"e_1_2_7_16_1","unstructured":"Onkologie der Arbeitsgemeinschaft der Wissenschaftlichen. 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Available from:https:\/\/register.awmf.org\/assets\/guidelines\/032\u2010024OLl_S033_Melanom\u2010Diagnostik\u2010Therapie\u2010Nachsorge_2020\u20102008.pdf[Last accessed March 18 2024]."},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2023.2203831"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2023.03.003"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.21614\/chirurgia.111.6.500"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"et","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.15434","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,6]],"date-time":"2024-08-06T04:20:53Z","timestamp":1722918053000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.15434"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,23]]},"references-count":18,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1111\/ddg.15434"],"URL":"https:\/\/doi.org\/10.1111\/ddg.15434","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,23]]},"assertion":[{"value":"2023-07-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}