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Supportive therapy refers to measures designed to alleviate and improve disease\u2010related symptoms, such as pain, in addition to disease\u2010specific treatments.<\/jats:p><jats:p>This review focuses on strategies for targeted pharmacological pain management, addressing contraindications, usage restrictions, dosing, dose adjustments, and potential drug interactions. While nonopioid analgesics are central to pain management, carefully selected opioids are also utilized. However, these may negatively affect patients' well\u2010being and treatment adherence due to side effects like constipation and nausea. 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