{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T22:11:12Z","timestamp":1791670272573,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T00:00:00Z","timestamp":1764288000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Hidradenitis suppurativa (HS) is a chronic, debilitating skin disease affecting approximately 0.1% of the German population. Patients with HS require substantial healthcare resource utilization. This study aimed to assess the economic burden associated with HS in Germany.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>Adults with HS and statutory health insurance were included if they had at least one outpatient or inpatient medical HS claim between August 1, 2015, and December 31, 2016. Patients were followed for up to 1\u00a0year, until a change of health service provider, the end of the study period (December 31, 2017), or death, whichever occurred first. Outcomes were measured during the follow\u2010up period and included all\u2010cause and HS\u2010related outpatient, inpatient, and medical claims as well as sick leave.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 1,941 patients were included in the HS study cohort, of whom 1,919 had healthcare resource claims during follow\u2010up. Overall, 37.0% of patients had outpatient dermatology visits, 3.6% had biologic therapy claims, 16.1% underwent HS\u2010related surgery, and 6.2% had HS\u2010related inpatient visits during follow\u2010up. Among patients without prior biologic medication use, 24.0% of HS\u2010related costs were attributable to inpatient visits. Medication, outpatient visits, and therapeutic appliances or aids accounted for 54.5%, 18.0%, and 3.5% of costs, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The majority of HS\u2010related claims were attributable to medications, followed by inpatient treatment, underscoring the need for therapies that provide long\u2010term effectiveness and tolerability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ddg.15901","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T14:23:04Z","timestamp":1764339784000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Economic burden of hidradenitis suppurativa based on healthcare resource utilization: German claims data analysis"],"prefix":"10.1111","author":[{"given":"Falk G.","family":"Bechara","sequence":"first","affiliation":[{"name":"Department of Dermatology Venereology and Allergology St. Josef Hospital Ruhr University Bochum  Bochum Germany"},{"name":"ICH \u2013 International Center for Hidradenitis Suppurativa\/Acne Inversa Ruhr University Bochum  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Tran","sequence":"additional","affiliation":[{"name":"UCB  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Kiri","sequence":"additional","affiliation":[{"name":"UCB  Slough UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romy","family":"Bley","sequence":"additional","affiliation":[{"name":"UCB  Monheim am Rhein Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Schl\u00fcter","sequence":"additional","affiliation":[{"name":"UCB  Monheim am Rhein 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