{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T20:58:18Z","timestamp":1781816298256,"version":"3.54.5"},"reference-count":40,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Primary cutaneous lymphomas (PCL) are primarily composed of cutaneous T\u2010cell lymphomas (CTCL), followed by cutaneous B\u2010cell lymphomas (CBCL). This study aimed to assess the incidence and survival rates of PCL in Germany.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed data from the North Rhine\u2010Westphalia Cancer Registry (2008\u20132021), which covers a population of 18 million. Age\u2010standardized incidence rates and relative survival were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The analysis included 3,853 patients with newly diagnosed PCL. Of these, 69.5% were CTCL, and 24.9% were CBCL. The age\u2010standardized incidence of PCL was 10.8 per million person\u2010years. The incidence of both CTCL and CBCL increased over time. PCL cases were also identified in children. The overall five\u2010year relative survival for PCL was 89% (95% CI: 87\u201392%), with CTCL patients having a survival rate of 91% (95% CI: 88\u201394%) and CBCL patients of 86% (95% CI: 81\u201391%). Among patients with S\u00e9zary syndrome, the five\u2010year relative survival was 53% (95%: CI:29\u201377%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study represents the largest population\u2010based analysis of PCL in Germany, including both adults and children. The incidence of PCL was higher than previously reported. Additionally, we present the first survival data for PCL in Germany, revealing a notably higher survival probability for patients with S\u00e9zary syndrome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ddg.15904","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T04:46:15Z","timestamp":1765601175000},"page":"351-358","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Recent trends of incidence and mortality of cutaneous lymphomas in Germany"],"prefix":"10.1111","volume":"24","author":[{"given":"Khodr Cheikh","family":"El Najjarine","sequence":"first","affiliation":[{"name":"Department of Dermatology HELIOS Klinikum Krefeld Academic Teaching Hospital of the University of Aachen  Krefeld Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-1831-2542","authenticated-orcid":false,"given":"Hiltraud","family":"Kaj\u00fcter","sequence":"additional","affiliation":[{"name":"Cancer Registry of North Rhine\u2010Westphalia  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3729-4447","authenticated-orcid":false,"given":"Ina","family":"Wellmann","sequence":"additional","affiliation":[{"name":"Cancer Registry of North Rhine\u2010Westphalia  Bochum Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6363-9061","authenticated-orcid":false,"given":"Andreas","family":"Stang","sequence":"additional","affiliation":[{"name":"Cancer Registry of North Rhine\u2010Westphalia  Bochum Germany"},{"name":"Institute for Medical Informatics Biometry and Epidemiology University Hospital Essen University of Duisburg\u2010Essen  Essen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7898-9432","authenticated-orcid":false,"given":"Chalid","family":"Assaf","sequence":"additional","affiliation":[{"name":"Department of Dermatology HELIOS Klinikum Krefeld Academic Teaching Hospital of the University of Aachen  Krefeld Germany"},{"name":"Institute for Molecular Medicine Medical School Hamburg  Hamburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-11-881268"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-662-49544-5_109"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00292-014-2017-9"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.08.033"},{"key":"e_1_2_7_6_1","unstructured":"DummerR StadlerR SterryW.Deutsche Leitlinie: Kutane Lymphome. 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