{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T11:01:13Z","timestamp":1791198073492,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T00:00:00Z","timestamp":1759708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T00:00:00Z","timestamp":1759708800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as \u201clow\u2010risk\u201d and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts. However, in very rare cases, HPV42 has also been identified in invasive genital tumors, particularly cervical carcinomas. In the case series presented here, HPV42 was detected in anogenital warts, a digital squamous cell carcinoma in situ, and a lymphogenously metastasized digital papillary adenocarcinoma (DPA). In the latter tumor entity, HPV42 was recently identified as the potential causative agent. Depending on the infected cell population, HPV42 can give rise to both benign lesions (anogenital warts and the rare cervicovaginal \u201cseborrheic keratosis\u2010like\u201d lesion) and malignant lesions (anogenital and digital carcinomas, as well as the highly aggressive DPA). HPV42 can therefore be considered as potentially carcinogenic. With the currently available nonavalent HPV vaccine over 90% of HPV\u2010related tumors and anogenital warts can be prevented, but not HPV42\u2010induced lesions. These tumors will therefore not be suppressed by the current vaccination programs, even not in countries with high vaccination rates.<\/jats:p>","DOI":"10.1111\/ddg.15981","type":"journal-article","created":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T07:05:11Z","timestamp":1759734311000},"page":"1412-1416","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["HPV42 \u2013 a human papillomavirus classified as a low\u2010risk type with oncogenic potential"],"prefix":"10.1111","volume":"24","author":[{"given":"Sven Niklas","family":"Burmann","sequence":"first","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Helios St. Elisabeth Hospital Oberhausen University Witten\/Herdecke  Oberhausen Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Wieland","sequence":"additional","affiliation":[{"name":"Institute of Virology National Reference Center for Papilloma\u2010 and Polyomaviruses University of Cologne Medical Faculty and University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffi","family":"Silling","sequence":"additional","affiliation":[{"name":"Institute of Virology National Reference Center for Papilloma\u2010 and Polyomaviruses University of Cologne Medical Faculty and University Hospital Cologne  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Oellig","sequence":"additional","affiliation":[{"name":"Institute of Pathology  M\u00fclheim an der Ruhr Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1807-8258","authenticated-orcid":false,"given":"David","family":"Chromy","sequence":"additional","affiliation":[{"name":"University Department of Dermatology Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Hyun","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Helios St. Johannes Klinik Duisburg  Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thilo","family":"Gambichler","sequence":"additional","affiliation":[{"name":"Department of Dermatology Christian Hospital Unna  Unna Germany"},{"name":"Department of Dermatology Klinikum Dortmund gGmbH University of Witten\/Herdecke  Dortmund Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2275-499X","authenticated-orcid":false,"given":"Alexander","family":"Kreuter","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology Helios St. Elisabeth Hospital Oberhausen University Witten\/Herdecke  Oberhausen Germany"},{"name":"Department of Dermatology Venereology and Allergology Helios St. Johannes Klinik Duisburg  Duisburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,10,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021641"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2010.02.002"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00105-023-05282-8"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.24116"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(87)90130-9"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-1375"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/0956462412474538"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31828b6be4"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-22-0489"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.15719"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28979"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-2913"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PGP.0000000000000835"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2011.03.011"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000517479"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000002420"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2009.09343.x"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2010.02.057"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1987.tb00488.x"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001483"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-022-01094-8"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000002096"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/cup.14782"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31826320ec"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/femsre\/fuae029"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1010790"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41541-024-00914-z"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"de","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.15981","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ddg.15981","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.15981","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:15:02Z","timestamp":1791195302000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.15981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,6]]},"references-count":27,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/ddg.15981"],"URL":"https:\/\/doi.org\/10.1111\/ddg.15981","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,6]]},"assertion":[{"value":"2025-06-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}