{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T11:06:46Z","timestamp":1781089606088,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Lip squamous cell carcinoma (SCC) accounts for approximately 30% of oral malignancies. Delayed diagnosis worsens the prognosis, leading to tumor growth, regional lymph node involvement, distant metastasis, and the need for invasive therapy. Dermoscopy is a practical, low\u2010cost, and non\u2010invasive diagnostic tool used to detect skin tumors. This review analyzed the common dermoscopic features of lip SCC and actinic cheilitis (AC). A search of MEDLINE, EMBASE, and Web of Science was made for original dermatoscopy studies. Pooled proportions were calculated using a random\u2010effects model (95% CI). Eleven studies were included: 325 patients, 205 lip SCCs, and 122 ACs. Key dermoscopic findings in lip SCCs were white structureless areas 61.9%, ulceration 59.3%, white halos 57.7%, keratin scales 54.98%, pinkish\u2010red background 50.5%, whitish\u2010yellow colors 41.8%, and shiny white streaks 24.5%. Polymorphous vessels were found in 55.8%, and monomorphous in 44.1%. Vessel morphology was hairpin 30.90%, serpentine 22.27%, dotted 21.46%, and glomerular 11.20%. ACs exhibited white halos in 66.14% of cases, white structureless areas in 59.62%, white scales in 57.90%, yellow scales in 30.14%, ulceration in 32.43%, white circles in 9.94%, and had polymorphous (72.93%), hairpin (30.83%), or dotted (20.71%) vessels. Dermoscopy aids early detection of lip SCC and AC, though overlapping features can limit accurate distinction. Histopathological confirmation remains essential in difficult cases, and further studies should explore subgroup\u2010specific dermoscopic patterns.<\/jats:p>","DOI":"10.1111\/ddg.15982","type":"journal-article","created":{"date-parts":[[2025,12,20]],"date-time":"2025-12-20T06:42:16Z","timestamp":1766212936000},"page":"158-174","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Dermoscopic features of lip squamous cell carcinoma and actinic cheilitis: A systematic review and meta\u2010analysis"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3760-8294","authenticated-orcid":false,"given":"Isabelle Albuquerque","family":"Reis","sequence":"first","affiliation":[{"name":"Federal University of Para\u00edba (UFPB)  Para\u00edba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4941-4146","authenticated-orcid":false,"given":"Lilia Maria Lima de","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Harvard T.H. Chan School of Public Health \u2013 Post\u2010graduate Program ECPE  Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1tima Maria Thaiz da Fonte Gomes da","family":"Silva","sequence":"additional","affiliation":[{"name":"Federal University of Para\u00edba (UFPB)  Para\u00edba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyria de Oliveira","family":"Rosa","sequence":"additional","affiliation":[{"name":"Esp\u00edrito Santo's University Center (UNESC)  Esp\u00edrito Santo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabrielle de Lacerda Dantas","family":"Henrique","sequence":"additional","affiliation":[{"name":"Federal University of Para\u00edba (UFPB)  Para\u00edba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nath\u00e1lia Freire","family":"Borba","sequence":"additional","affiliation":[{"name":"Federal University of Para\u00edba (UFPB)  Para\u00edba 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Abreu","family":"Fraga\u2010Braghiroli","sequence":"additional","affiliation":[{"name":"Department of Dermatology Miami Cancer Institute Baptist Health South Florida  Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.3455"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-014-3415-6"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116000499"},{"key":"e_1_2_8_5_1","volume-title":"AJCC cancer staging manual","author":"Amin 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