{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T08:15:56Z","timestamp":1788509756007,"version":"build-2803163510"},"reference-count":42,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T00:00:00Z","timestamp":1788480000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Objectives<\/jats:title>\n                    <jats:p>Achieving sustained drug adherence in psoriasis remains challenging despite effective therapies. This exploratory study aims to investigate the care situation and factors associated with drug adherence in patients with moderate\u2010to\u2010severe psoriasis vulgaris (PsO).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>A single\u2010center study was conducted at the University Medical Center Regensburg, Germany, comprising a retrospective analysis of 312 patient records of individuals treated between 01\/2023 and 06\/2023 and a prospective questionnaire\u2010based cross\u2010sectional survey of 62 patients treated between 10\/2023 and 03\/2024. Sociodemographic, clinical, and treatment\u2010related variables and quality of life (QoL) were analyzed descriptively and explored using inferential statistics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Most patients resided outside the urban care center (82.1% retrospective, 81.0% prospective). Approximately three quarters were adherent (75.0% and 72.4%, respectively). Non\u2010adherence was associated with occupational status, medication class, adverse events, and nicotine use. Patient\u2010reported reasons included administrative barriers (43.8%), financial burden, and adverse events (18.8% each). Non\u2010adherent patients tended to report higher disease burden and lower QoL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Drug adherence in moderate\u2010to\u2010severe PsO is associated with socioeconomic and therapy\u2010related factors. Targeted patient\u2010centered strategies may help improve long\u2010term adherence, particularly in vulnerable patient groups, optimize overall outcomes, and reduce financial burden on the healthcare system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ddg.70390","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T07:43:47Z","timestamp":1788507827000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors associated with drug adherence in psoriasis: a\u00a0single\u2010center, retrospective, questionnaire\u2010based exploratory study in Bavaria"],"prefix":"10.1111","author":[{"given":"Negahr","family":"Jalili\u2010Tazeshahri","sequence":"first","affiliation":[{"name":"Department of Dermatology University Medical Center Regensburg  Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gunnar","family":"Huppertz","sequence":"additional","affiliation":[{"name":"Center for Clinical Studies University Medical Center Regensburg  Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernadett","family":"Kurz","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Regensburg  Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Isabel","family":"von Eichborn","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Regensburg  Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Berneburg","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Regensburg  Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim","family":"Maisch","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Regensburg  Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2069-0486","authenticated-orcid":false,"given":"Dennis","family":"Niebel","sequence":"additional","affiliation":[{"name":"Department of Dermatology University Medical Center Regensburg  Regensburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,4]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Fitzpatrick's Dermatology in General Medicine","author":"Goldsmith LA","year":"2012"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0804595"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.12106"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.4006"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.140.4.408"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000329026"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1547-5069.2003.tb00001.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12039"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-0073"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2024.03.1951"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m1590"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/14737167.2018.1512408"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-019-1014-8"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.03.045"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11061506"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13452"},{"key":"e_1_2_9_18_1","volume-title":"Eine Querschnittsbefragung am Universit\u00e4tsklinikum Regensburg zur Versorgungssituation und Lebensqualit\u00e4t bei Patienten mit Psoriasis vulgaris","author":"Schwiersch M","year":"2019"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/ddg.14508_g"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080633"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2012.04525.x"},{"issue":"1","key":"e_1_2_9_22_1","first-page":"11","article-title":"Psoriasis \u2013 new insights into pathogenesis and treatment","volume":"106","author":"Mrowietz U","year":"2009","journal-title":"Dtsch Arztebl Int"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2230.2000.00588.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2010.07358_supp.x"},{"key":"e_1_2_9_25_1","unstructured":"Statista GmbH.Statistisches Datenportal Deutschland. 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