{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:42:15Z","timestamp":1792654935759,"version":"4.5.0"},"reference-count":22,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:00:00Z","timestamp":1792627200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J Deutsche Derma Gesell"],"DOI":"10.1111\/ddg.70554","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:31:33Z","timestamp":1792654293000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Triple therapy with deucravacitinib, methotrexate, and dexamethasone unsuccessful for refractory lichen planus"],"prefix":"10.1111","author":[{"given":"Neda","family":"Cramer","sequence":"first","affiliation":[{"name":"Department of Dermatology Venereology and Allergology University Medical Center G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline Sophie","family":"Jonas","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology University Medical Center G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0698-4130","authenticated-orcid":false,"given":"Michael P.","family":"Sch\u00f6n","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology University Medical Center G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rotraut","family":"M\u00f6ssner","sequence":"additional","affiliation":[{"name":"Department of Dermatology Venereology and Allergology University Medical Center G\u00f6ttingen, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,22]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/742826","article-title":"Cutaneous and Mucosal Lichen Planus: A Comprehensive Review of Clinical Subtypes, Risk Factors, Diagnosis, and Prognosis","volume":"2014","author":"Gorouhi F","year":"2014","journal-title":"Sci World J"},{"issue":"7","key":"e_1_2_4_3_1","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1111\/jdv.16464","article-title":"European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology","volume":"34","author":"Ioannides D","year":"2020","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"e_1_2_4_4_1","volume-title":"Fachinformation: Prednisolon acis\u00ae","author":"Acis Arzneimittel GmbH"},{"key":"e_1_2_4_5_1","volume-title":"Fachinformation: Acicutan\u00ae 10 mg\/25 mg Hartkapseln","author":"Dermapharm AG"},{"issue":"8","key":"e_1_2_4_6_1","doi-asserted-by":"crossref","first-page":"3098","DOI":"10.1080\/09546634.2022.2116926","article-title":"JAK inhibitors in lichen planus: a review of pathogenesis and treatments","volume":"33","author":"Motamed\u2010Sanaye A","year":"2022","journal-title":"J Dermatol Treat"},{"key":"e_1_2_4_7_1","volume-title":"SOTYKTU\u00ae (deucravacitinib) 6 mg film\u2010coated tablets: Summary of product characteristics","author":"Bristol\u2010Myers Squibb","year":"2024"},{"issue":"4","key":"e_1_2_4_8_1","doi-asserted-by":"crossref","DOI":"10.1111\/exd.15080","article-title":"TYK2 inhibition with deucravacitinib ameliorates erosive oral lichen planus","volume":"33","author":"Stolte KN","year":"2024","journal-title":"Exp Dermatol"},{"key":"e_1_2_4_9_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.jdcr.2023.12.006","article-title":"Treatment of oral lichen planus using deucravacitinib","volume":"44","author":"Vu M","year":"2024","journal-title":"JAAD Case Rep"},{"key":"e_1_2_4_10_1","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jdcr.2024.06.013","article-title":"Treatment of hypertrophic lichen planus using deucravacitinib","volume":"51","author":"Sood S","year":"2024","journal-title":"JAAD Case Rep"},{"issue":"10","key":"e_1_2_4_11_1","article-title":"A Case of Extensive Lichen Planus Treated With Deucravacitinib","volume":"16","author":"Ball GD","year":"2024","journal-title":"Cureus"},{"issue":"1","key":"e_1_2_4_12_1","article-title":"Central role of intestinal epithelial glucocorticoid receptor in alcohol\u2010 and corticosterone\u2010induced gut permeability and systemic response","volume":"36","author":"Shukla PK","year":"2022","journal-title":"FASEB J Off Publ Fed Am Soc Exp Biol"},{"issue":"3","key":"e_1_2_4_13_1","first-page":"748","article-title":"11 beta\u2010Hydroxysteroid dehydrogenase deficiency and glucocorticoid status in patients with alcoholic and non\u2010alcoholic chronic liver disease","volume":"76","author":"Stewart PM","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"e_1_2_4_14_1","volume-title":"Updated recommendations to minimize the risks of malignancies, serious adverse cardiovascular events, serious infections, venous thromboembolism, and mortality associated with the use of Janus kinase inhibitors (JAKi)","author":"AbbVie G","year":"2023"},{"issue":"1","key":"e_1_2_4_15_1","doi-asserted-by":"crossref","DOI":"10.1155\/dth\/8752339","article-title":"Drug Survival in the Treatment of Mucosal Lichen Planus: A Retrospective Multicenter Study","volume":"2025","author":"Cramer N","year":"2025","journal-title":"Dermatol Ther"},{"issue":"511","key":"e_1_2_4_16_1","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aav7561","article-title":"IFN\u2010\u03b3 enhances cell\u2010mediated cytotoxicity against keratinocytes via JAK2\/STAT1 in lichen planus","volume":"11","author":"Shao S","year":"2019","journal-title":"Sci Transl Med"},{"issue":"2","key":"e_1_2_4_17_1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1111\/exd.14226","article-title":"The inflammation in cutaneous lichen planus is dominated by IFN\u2010\u03d2 and IL\u201021\u2010A basis for therapeutic JAK1 inhibition","volume":"30","author":"Pietschke K","year":"2021","journal-title":"Exp Dermatol"},{"issue":"3","key":"e_1_2_4_18_1","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1177\/12034754231156100","article-title":"The Use of Janus Kinase Inhibitors for Lichen Planus: An Evidence\u2010Based Review","volume":"27","author":"Abduelmula A","year":"2023","journal-title":"J Cutan Med Surg"},{"key":"e_1_2_4_19_1","doi-asserted-by":"crossref","DOI":"10.1177\/11795476241237350","article-title":"Successful Treatment of Erosive Lichen Planus With Tofacitinib: A Case Series and Review of the Literature","volume":"17","author":"Mansouri P","year":"2024","journal-title":"Clin Med Insights Case Rep"},{"issue":"6","key":"e_1_2_4_20_1","doi-asserted-by":"crossref","DOI":"10.1111\/dth.12656","article-title":"Tofacitinib for the treatment of lichen planopilaris: A case series","volume":"31","author":"Yang CC","year":"2018","journal-title":"Dermatol Ther"},{"issue":"1","key":"e_1_2_4_21_1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jaad.2022.07.002","article-title":"Deucravacitinib versus placebo and apremilast in moderate to severe plaque psoriasis: Efficacy and safety results from the 52\u2010week, randomized, double\u2010blinded, placebo\u2010controlled phase 3 POETYK PSO\u20101 trial","volume":"88","author":"Armstrong AW","year":"2023","journal-title":"J Am Acad Dermatol"},{"issue":"502","key":"e_1_2_4_22_1","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaw1736","article-title":"Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain","volume":"11","author":"Burke JR","year":"2019","journal-title":"Sci Transl Med"},{"issue":"1","key":"e_1_2_4_23_1","doi-asserted-by":"crossref","first-page":"5678","DOI":"10.1038\/s41598-026-36506-1","article-title":"Evaluation of salivary interleukin 6 interleukin 1 beta and interferon gamma in oral and mucocutaneous lichen planus patients","volume":"16","author":"Hama PN","year":"2026","journal-title":"Sci Rep"}],"container-title":["JDDG: Journal der Deutschen Dermatologischen Gesellschaft"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.70554","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ddg.70554","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ddg.70554","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:31:37Z","timestamp":1792654297000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ddg.70554"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,22]]},"references-count":22,"alternative-id":["10.1111\/ddg.70554"],"URL":"https:\/\/doi.org\/10.1111\/ddg.70554","archive":["Portico"],"relation":{},"ISSN":["1610-0379","1610-0387"],"issn-type":[{"value":"1610-0379","type":"print"},{"value":"1610-0387","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,22]]},"assertion":[{"value":"2025-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"ddg.70554"}}