{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:54:46Z","timestamp":1775148886789,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,12,26]],"date-time":"2012-12-26T00:00:00Z","timestamp":1356480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p>Plexiform schwannoma is a benign peripheral nerve sheath tumor composed exclusively of <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>chwann cells arranged in a plexiform pattern. Most plexiform schwannomas are skin tumors and visceral localization is very rare. To our knowledge, there are six cases localized in visceral organs. We describe herein the first known case of plexiform schwannoma of the rectum resected by endoscopic submucosal dissection (<jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content>). A 77\u2010year\u2010old woman presented with a short history of anal pain. Sigmoidoscopy demonstrated a submucosal tumor, 20\u2009mm in diameter, of the rectum below the peritoneal reflection (<jats:styled-content style=\"fixed-case\">R<\/jats:styled-content>b). We resected the tumorby <jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content>. The tumor consisted of multiple white nodules in the submucosal layer. Microscopic examination revealed that the tumor was composed mainly of <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content>ntoni <jats:styled-content style=\"fixed-case\">A<\/jats:styled-content> tissue, compatible with conventional schwannoma. Immunohistochemically, the tumor was positive for <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>\u2010100, and negative for \u03b1\u2010smooth muscle actin, c\u2010kit and <jats:styled-content style=\"fixed-case\">CD<\/jats:styled-content>\u201034. No evidence of recurrence has been found in 2 years of follow up.<\/jats:p>","DOI":"10.1111\/den.12022","type":"journal-article","created":{"date-parts":[[2012,12,27]],"date-time":"2012-12-27T01:40:19Z","timestamp":1356572419000},"page":"113-116","source":"Crossref","is-referenced-by-count":17,"title":["Plexiform schwannoma of the rectum"],"prefix":"10.1111","volume":"26","author":[{"given":"Shinya","family":"Kawaguchi","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rei","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhiro","family":"Yamamura","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Oyamada","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyoe","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirofumi","family":"Fuke","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Ise Red Cross Hospital  Ise Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Yabana","sequence":"additional","affiliation":[{"name":"Department of Pathology Ise Red Cross Hospital  Ise Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,12,26]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-197809000-00165"},{"key":"e_1_2_5_3_1","first-page":"1075","article-title":"Giant plexiform schwannoma: Report of two cases with soft tissue and visceral involvement","volume":"11","author":"Hirose T","year":"1997","journal-title":"Mod. 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