{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T07:16:55Z","timestamp":1694589415919},"reference-count":13,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2013,4,25]],"date-time":"2013-04-25T00:00:00Z","timestamp":1366848000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2013,5]]},"abstract":"A 40\u2010year\u2010old man was referred to our hospital for detailed examination of a protuberant lesion in long\u2010segment B<\/jats:styled-content>arrett's esophagus (LSBE<\/jats:styled-content>). Under white light endoscopy (WLE<\/jats:styled-content>) the lesion appeared as a protuberant lesion with a rough surface and was diagnosed as 0\u2010IIa<\/jats:styled-content>\u2010type tumor suspected to be a well\u2010differentiated adenocarcinoma. A regular villous pattern was shown in the background mucosa of the LSBE<\/jats:styled-content> by narrow\u2010band imaging (NBI<\/jats:styled-content>) magnifying endoscopy (NBI\u2010ME<\/jats:styled-content>). However, a slightly irregular villous pattern was observed on the lateral side of the main lesion. Therefore, a 0\u2010IIa<\/jats:styled-content>\u2010type tumor was estimated to have a flatly lateral extension component (i.e. 0\u2010IIb<\/jats:styled-content> spreading). The 0\u2010IIb<\/jats:styled-content> spreading was unclear when using WLE<\/jats:styled-content>, but could be diagnosed by NBI\u2010ME<\/jats:styled-content> based on the surface pattern differences. Markings were placed outside the edge of the flatly lateral extension, and endoscopic submucosal dissection was carried out.The pathological diagnosis of the protuberant lesion with flatly lateral spreading was well\u2010differentiated adenocarcinoma. The macroscopic type was 0\u2010IIa<\/jats:styled-content>+IIb<\/jats:styled-content>, 45\u2009\u00d7\u200943\u2009mm in size. The invasion depth was T1a<\/jats:styled-content> (deep muscularis mucosae). Lymphatic and venous invasions were negative; horizontal and vertical margins were negative. In conclusion, NBI\u2010ME<\/jats:styled-content> was useful for the diagnosis of the flatly lateral extension of this 0\u2010IIa<\/jats:styled-content>+IIb<\/jats:styled-content> esophageal adenocarcinoma in B<\/jats:styled-content>arrett's esophagus. Further investigations with many cases are necessary.<\/jats:p>","DOI":"10.1111\/den.12113","type":"journal-article","created":{"date-parts":[[2013,4,26]],"date-time":"2013-04-26T01:12:22Z","timestamp":1366938742000},"page":"184-189","source":"Crossref","is-referenced-by-count":4,"title":["B<\/scp>arrett's esophageal adenocarcinoma diagnosed by narrow\u2010band imaging magnifying endoscopy"],"prefix":"10.1111","volume":"25","author":[{"given":"Akiko","family":"Takahashi","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Saku Central Hospital Nagano Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tsuneo","family":"Oyama","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Saku Central Hospital Nagano Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,4,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.4680"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1214594"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.08.007"},{"key":"e_1_2_5_5_1","first-page":"933","article-title":"Histopathological diagnosis of gastric cancers by magnified endoscopy with NBI","volume":"46","author":"Oyama T","year":"2011","journal-title":"Stom. 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