{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T07:08:27Z","timestamp":1770966507988,"version":"3.50.1"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,8,13]],"date-time":"2013-08-13T00:00:00Z","timestamp":1376352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>A double\u2010balloon (<jats:styled-content style=\"fixed-case\">DB<\/jats:styled-content>) endoscope can be selectively inserted into the afferent loop to carry out endoscopic retrograde cholangiopancreatography (<jats:styled-content style=\"fixed-case\">ERCP<\/jats:styled-content>) in patients with surgically altered anatomy, allowing various types of endoscopic treatments for pancreaticobiliary diseases to be successfully carried out. In order to make such a lengthy procedure more comfortable and safe, sedatives and carbon dioxide (<jats:styled-content style=\"fixed-case\"><jats:roman>CO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content>) insufflation are widely used for gastrointestinal endoscopy. However, these techniques can increase the risk of <jats:styled-content style=\"fixed-case\"><jats:roman>CO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> retention. Recently, a new sensor for transcutaneous measurement of partial pressure of carbon dioxide (<jats:styled-content style=\"fixed-case\"><jats:roman>PCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content>) has been introduced. The aim of the present study was to evaluate the changes in transcutaneous <jats:styled-content style=\"fixed-case\"><jats:roman>PCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> (<jats:styled-content style=\"fixed-case\"><jats:roman>PtcCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content>) during <jats:styled-content style=\"fixed-case\">DB\u2010ERCP<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\"><jats:roman>CO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> insufflation under conscious sedation and assess any complications related to sedation and <jats:styled-content style=\"fixed-case\"><jats:roman>CO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> insufflation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 312 patients underwent <jats:styled-content style=\"fixed-case\">DB\u2010ERCP<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\"><jats:roman>CO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> insufflation at our hospital between <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>arch 2009 and <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content>ecember 2012. The patients were moderately sedated using midazolamwith or without pentazocine. <jats:styled-content style=\"fixed-case\"><jats:roman>PtcCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> was measured by a non\u2010invasive sensor throughout <jats:styled-content style=\"fixed-case\">DB\u2010ERCP<\/jats:styled-content> in all patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean peak <jats:styled-content style=\"fixed-case\"><jats:roman>PtcCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> during the procedure was significantly higher than the mean <jats:styled-content style=\"fixed-case\"><jats:roman>PtcCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> value before and after <jats:styled-content style=\"fixed-case\">DB\u2010ERCP<\/jats:styled-content>. Body mass index, procedure time and dose of pentazocine were significantly higher in the <jats:styled-content style=\"fixed-case\"><jats:roman>CO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> retention group (peak <jats:styled-content style=\"fixed-case\"><jats:roman>PtcCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content>\u2009\u2265\u200950\u2009mm<jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>g). <jats:styled-content style=\"fixed-case\"><jats:roman>CO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> narcosis was observed in one case.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">DB\u2010ERCP<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\"><jats:roman>CO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> insufflation under conscious sedation might have the potential to increase the risk of <jats:styled-content style=\"fixed-case\"><jats:roman>CO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> retention. Hence, non\u2010invasive and continuous <jats:styled-content style=\"fixed-case\"><jats:roman>PtcCO<\/jats:roman><jats:sub>2<\/jats:sub><\/jats:styled-content> measurement is useful for early detection of hypercapnia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.12155","type":"journal-article","created":{"date-parts":[[2013,8,14]],"date-time":"2013-08-14T04:53:23Z","timestamp":1376456003000},"page":"436-441","source":"Crossref","is-referenced-by-count":4,"title":["Transcutaneous monitoring of partial pressure of carbon dioxide during endoscopic retrograde cholangiopancreatography using a double\u2010balloon endoscope with carbon dioxide insufflation under conscious sedation"],"prefix":"10.1111","volume":"26","author":[{"given":"Hideaki","family":"Miyoshi","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Kansai Medical University  Osaka 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