{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T13:42:54Z","timestamp":1773236574580,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,9,30]],"date-time":"2013-09-30T00:00:00Z","timestamp":1380499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2014,5]]},"abstract":"Background and Aim<\/jats:title>Endoscopic diagnosis of stomach mucosa\u2010associated lymphoid tissue (MALT<\/jats:styled-content>) lymphoma is often difficult because few specific findings are indicated. Even when MALT<\/jats:styled-content> lymphoma is suspected by endoscopy, it is still difficult to make a definitive diagnosis by biopsy because lymphoma cells sometimes distribute unevenly. We previously reported that a tree\u2010like appearance (TLA<\/jats:styled-content>) is a characteristic finding of MALT<\/jats:styled-content> lymphoma by narrow\u2010band imaging (NBI<\/jats:styled-content>) magnifying endoscopy and it is valuable in the selection of an optimal biopsy site in MALT<\/jats:styled-content> lymphoma. Here, we study the frequency of TLA<\/jats:styled-content> and evaluate the relationship between the response to eradication therapy and TLA<\/jats:styled-content> in MALT<\/jats:styled-content> lymphoma.<\/jats:p><\/jats:sec>Methods<\/jats:title>We retrospectively examined the clinical background, endoscopic findings, response to eradication therapy, and H<\/jats:styled-content>elicobacter pylori<\/jats:italic> infection status of 16 patients diagnosed with MALT<\/jats:styled-content> lymphoma who were referred to our hospital from A<\/jats:styled-content>pril 2007 to A<\/jats:styled-content>ugust 2012. The regimen for eradicationtherapy consisted of rabeprazole, with amoxicillin and clarithromycin, all given for 7 days.<\/jats:p><\/jats:sec>Results<\/jats:title>TLA<\/jats:styled-content> was found in 75% (12\/16) and H<\/jats:styled-content>.\u2009pylori<\/jats:italic> infection in 75% (12\/16) of patients diagnosed with MALT<\/jats:styled-content> lymphoma by NBI<\/jats:styled-content> magnifying endoscopy. In all complete regression (CR<\/jats:styled-content>) patients after eradication treatment, the TLA<\/jats:styled-content> finding had disappeared (100%); however, in the non\u2010CR<\/jats:styled-content> patients, TLA<\/jats:styled-content> remained the same as before the eradication therapy (P<\/jats:italic>\u2009=\u20090.002).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>These results suggest that NBI<\/jats:styled-content> magnifying endoscopy may be useful not only in the diagnosis but also in the evaluation of the response to eradication therapy of MALT<\/jats:styled-content> lymphoma of the stomach.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.12169","type":"journal-article","created":{"date-parts":[[2013,10,12]],"date-time":"2013-10-12T01:42:50Z","timestamp":1381542170000},"page":"358-364","source":"Crossref","is-referenced-by-count":21,"title":["Is narrow\u2010band imaging useful for histological evaluation of gastric mucosa\u2010associated lymphoid tissue lymphoma after treatment?"],"prefix":"10.1111","volume":"26","author":[{"given":"Kouichi","family":"Nonaka","sequence":"first","affiliation":[{"name":"Department of Gastroenterology Saitama Medical University International Medical Center Hidaka Japan"},{"name":"Department of Gastroenterology NTT Medical Center Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Ohata","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology NTT Medical Center Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Matsuhashi","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology NTT Medical Center Tokyo Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michio","family":"Shimizu","sequence":"additional","affiliation":[{"name":"Department of Pathology Saitama Medical University International Medical Center Hidaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin","family":"Arai","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Saitama Medical University International Medical Center Hidaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshimitsu","family":"Hiejima","sequence":"additional","affiliation":[{"name":"Graduate School of Healthcare Tokyo Healthcare University Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroto","family":"Kita","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology Saitama Medical University International Medical Center Hidaka 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