{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T17:30:35Z","timestamp":1760549435833},"reference-count":15,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,10,31]],"date-time":"2013-10-31T00:00:00Z","timestamp":1383177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Endoscopic submucosal dissection (<jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content>) is a complex procedure and is associated with significant risks. The aims of this pilot study were to study feasibility and procedural times of gastric <jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content> using a novel gel and endoscopic scissors in a porcine model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Simulated 3\u2010cm gastric submucosal lesions were created in a porcine model. Subsequently, viscous gel was injected into the created bleb. A needle knife was used to create an initial incision when needed. Endoscopic scissors were then used for circumferential incision around the simulated submucosal lesions. The inserted coil (i.e. submucosal lesion) was then removed. The submucosal surface was carefully examined for signs of injury. Procedural times were recorded.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content> was carried out in four consecutive pigs using the \u2018Scissorhands\u2019 technique. A small submucosal incision was created a using needle knife in the first pig and electrocauterywas not used in the remaining three pigs. Circumferential incision using the scissors was done successfully in all pigs. Submucosal dissection was not required in any case. \u2018Auto\u2010dissection\u2019 of created lesions by the gel was noted to be complete in all cases. Inserted coils were noted in the submucosal space during all experiments and were removed. All lesions were successfully resected en bloc. The mean procedure time was 19\u2009min (range 13\u201322\u2009min).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The combined technique of endoscopic scissors for circumferential incision and viscous gel for submucosal dissection permitted easy, safe and efficient gastric <jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content>. Electrocautery may be avoided and its consequent adverse events (e.g. perforation).<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.12186","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T08:06:38Z","timestamp":1383293198000},"page":"365-368","source":"Crossref","is-referenced-by-count":2,"title":["Pilot study of \u2018<scp>S<\/scp>cissorhands\u2019 technique for gastric endoscopic submucosal dissection using novel gel and endoscopic scissors in a porcine model (with video)"],"prefix":"10.1111","volume":"26","author":[{"given":"Mouen A.","family":"Khashab","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Payal","family":"Saxena","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reem","family":"Sharaiha","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed","family":"Messallam","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Venkata S.","family":"Akshintala","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vikesh K.","family":"Singh","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne Marie","family":"Lennon","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcia I.","family":"Canto","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anthony N.","family":"Kalloo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pankaj J.","family":"Pasricha","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine The Johns Hopkins Medical Institutions  Baltimore USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10,31]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.48.2.225"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(88)71327-9"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-41516"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2007.03.1059"},{"key":"e_1_2_6_6_1","first-page":"299","article-title":"Superficial oeso\u2010gastric cancer and endoscopic mucosal resection: The pathologist's approach","volume":"69","author":"Jouret A","year":"2006","journal-title":"Acta Gastroenterol. 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