{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T02:23:07Z","timestamp":1776910987308,"version":"3.51.2"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T00:00:00Z","timestamp":1395273600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>To compare the efficacy and tolerability of a low\u2010volume (2\u2010<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>) polyethylene glycol (<jats:styled-content style=\"fixed-case\">PEG<\/jats:styled-content>) regimen for colonoscopy compared to single (4\u2010<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>) or split\u2010dose (2\u2010<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\u2009+\u20092\u2010<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>) regimens.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In\u2010hospital patients who were candidates for colonoscopy were randomly assigned to: group 1 single\u2010dose (<jats:styled-content style=\"fixed-case\">PEG<\/jats:styled-content> 4\u2009<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content> the day before the study, <jats:italic>n<\/jats:italic>\u2009=\u200960); group 2: split\u2010dose (2\u2009<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content> the day before and 2\u2009<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content> on the day of the procedure, <jats:italic>n<\/jats:italic>\u2009=\u200961); and group 3: low\u2010volume 2\u2010<jats:styled-content style=\"fixed-case\">L PEG<\/jats:styled-content> solution (the day of the procedure, <jats:italic>n<\/jats:italic>\u2009=\u200959). A blinded evaluation of the quality of colonic preparation was assessed by the <jats:styled-content style=\"fixed-case\">B<\/jats:styled-content>oston bowel preparation scale.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Satisfactory bowel preparation of the right colon was more frequently reported for group 3 than for group 1 (70% <jats:italic>vs<\/jats:italic> 53%, <jats:italic>P<\/jats:italic>\u2009=\u20090.045), in the transverse colon it was 82% versus 69% (<jats:italic>P<\/jats:italic>\u2009=\u20090.032), and on the left side of the colon it was 80% versus 67.7% (<jats:italic>P<\/jats:italic>\u2009=\u20090.028). Compared to group 2, satisfactory bowel preparation in group 3 was similar in the transverse colon and left colon. Nausea, vomiting, and abdominal discomfort were less frequent in patients of group 3. Patients in group 3 had fewer sleep disorders and fewer hours of sleep loss compared to patients in the other groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Preparation with 2\u2009<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content> caused less abdominal discomfort and fewer sleep disorders. The split dose had a better quality of preparation in the right colon. Both preparations were clearly better than the 4\u2010<jats:styled-content style=\"fixed-case\">L<\/jats:styled-content> preparation.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.12265","type":"journal-article","created":{"date-parts":[[2014,3,20]],"date-time":"2014-03-20T08:52:56Z","timestamp":1395305576000},"page":"731-736","source":"Crossref","is-referenced-by-count":27,"title":["Efficacy and tolerability of low\u2010volume (2\u2009L) versus single\u2010 (4\u2009L) versus split\u2010dose (2\u2009L\u2009+\u20092\u2009L) polyethylene glycol bowel preparation for colonoscopy: Randomized clinical trial"],"prefix":"10.1111","volume":"26","author":[{"given":"F\u00e9lix I.","family":"T\u00e9llez\u2010\u00c1vila","sequence":"first","affiliation":[{"name":"Department of Endoscopy National Institute of Medical Sciences and Nutrition Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enrique","family":"Murcio\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Endoscopy National Institute of Medical Sciences and Nutrition Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Sa\u00fal","sequence":"additional","affiliation":[{"name":"Department of Endoscopy National Institute of Medical Sciences and Nutrition Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvador","family":"Herrera\u2010G\u00f3mez","sequence":"additional","affiliation":[{"name":"Department of Endoscopy National Institute of Medical Sciences and Nutrition Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Valdovinos\u2010Andraca","sequence":"additional","affiliation":[{"name":"Department of Endoscopy National Institute of Medical Sciences and Nutrition Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor","family":"Acosta\u2010Nava","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology National Institute of Medical Sciences and Nutrition Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Barreto","sequence":"additional","affiliation":[{"name":"Department of Endoscopy National Institute of Medical Sciences and Nutrition Salvador Zubir\u00e1n  Mexico City Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Elizondo\u2010Rivera","sequence":"additional","affiliation":[{"name":"Department of Endoscopy National Institute of Medical Sciences and Nutrition Salvador Zubir\u00e1n  Mexico City 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