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In the 6th week of steroid treatment, he developed high fever without other symptoms. Chest computed tomography revealed a nodular lesion in the lung. Sputum sample showed <jats:styled-content style=\"fixed-case\">G<\/jats:styled-content>ram\u2010positive, branching, filamentous bacteria, and a diagnosis of nocardiosis was suspected. Brain magnetic resonance imaging revealed multiple focal lesions which indicated dissemination of nocardiosis. Trimethoprim\u2010sulfamethoxazole was immediately started, which led to the disappearance of pulmonary and cerebral nocardiosis with alleviation of fever. Recently, oral steroid treatment has been widely used for the prevention of esophageal stricture. However, the present case indicates the risk of life\u2010threatening infection and the importance of close monitoring of this treatment.<\/jats:p>","DOI":"10.1111\/den.12317","type":"journal-article","created":{"date-parts":[[2014,5,29]],"date-time":"2014-05-29T10:12:07Z","timestamp":1401358327000},"page":"388-391","source":"Crossref","is-referenced-by-count":36,"title":["Disseminated nocardiosis during systemic steroid therapy for the prevention of esophageal stricture after endoscopic submucosal dissection"],"prefix":"10.1111","volume":"27","author":[{"given":"Tsukasa","family":"Ishida","sequence":"first","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Graduate School of Medicine Kobe University  Kobe Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshinori","family":"Morita","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Graduate School of Medicine Kobe 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