{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T21:31:04Z","timestamp":1791149464062,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,10,28]],"date-time":"2014-10-28T00:00:00Z","timestamp":1414454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2015,3]]},"abstract":"<jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Endoscopic submucosal dissection (<jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content>) is gaining worldwide recognition as valuable alternative to treat early colorectal neoplasia. Although the method is perceived as technically difficult and carries a higher risk of complications than conventional endoscopy, the oncological results are very promising. Herein we aim to present the treatment outcomes of <jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content> for lesions in the colon and rectum at the beginning of our learning curve.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Seventy consecutive cases of colorectal <jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content> carried out in our center between <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>une 2013 and <jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>ay 2014 were analyzed. Effectiveness of dissection, complications and tumor recurrence after 3 months of treatment were investigated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the 70 <jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content> procedures, 39 were in the rectum, 10 in the sigmoid, eight in the descending colon, six in the ascending colon and seven in the cecum. Average size of removed tumors was 38.1\u2009mm. In 50 cases, en\u2010block resection was achieved. In this group, 97% cases were <jats:styled-content style=\"fixed-case\">R0<\/jats:styled-content> resection. Perforation occurred in four cases (5.7%) of which three were managed with endoclips. In four cases, significant bleeding occurred. In a follow\u2010up examination, two of 41 patients (4.9%) had recurrent adenoma that was successfully endoscopically removed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results confirm that <jats:styled-content style=\"fixed-case\">ESD<\/jats:styled-content> is an effective and safe modality for treatment of colorectal epithelial neoplasia in the colon and rectum even at the beginning of the learning curve. After proper training, results in <jats:styled-content style=\"fixed-case\">E<\/jats:styled-content>urope and <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apan may be comparable.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.12353","type":"journal-article","created":{"date-parts":[[2014,9,2]],"date-time":"2014-09-02T11:46:29Z","timestamp":1409658389000},"page":"368-373","source":"Crossref","is-referenced-by-count":34,"title":["Safe and efficient colorectal endoscopic submucosal dissection in <scp>E<\/scp>uropean settings: <scp>I<\/scp>s successful implementation of the procedure possible?"],"prefix":"10.1111","volume":"27","author":[{"given":"Michal","family":"Spychalski","sequence":"first","affiliation":[{"name":"General and Colorectal Surgery Department Medical University  Lodz Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Dziki","sequence":"additional","affiliation":[{"name":"General and Colorectal Surgery Department Medical University  Lodz Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21166"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ypmed.2014.02.010","article-title":"Colorectal cancer prevention in Europe: Burden of disease and status of screening programs","volume":"62","author":"Altobelli E","journal-title":"Prev. 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