{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T22:11:00Z","timestamp":1771971060062,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,9,19]],"date-time":"2016-09-19T00:00:00Z","timestamp":1474243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:p>Although regular colonoscopy surveillance is recommended for patients with Lynch syndrome (LS) who underwent partial colectomy, the appropriate interval has not been determined. We report a case of colorectal cancer (CRC) detected by short\u2010interval surveillance colonoscopy (SC) in a patient with LS having a past history of partial colectomy. A 65\u2010year\u2010old man underwent sigmoidectomy for advanced CRC. His family history revealed that his two younger brothers had CRC in their twenties and thirties, respectively, and the patient met with the criteria in the Revised Bethesda Guidelines. After confirming the loss of MSH2 protein expression in the primary tumor, subsequent genetic testing showed germline mutation with a large deletion of exon 7\u201314 in the <jats:italic>MSH2<\/jats:italic> gene, indicating a diagnosis of LS. After the diagnosis of LS, the patient underwent annual SC. Three years after the initial surgery, superficial submucosal invasive cancer was detected. Subsequently, SC after a 6\u2010month interval revealed a deep submucosal invasive cancer (7\u00a0mm in diameter). Although additional surgery was recommended, considering his comorbidities, regular SC rather than colectomy was selected. Even shorter\u2010interval SC carried out within a year is not sufficient to detect endoscopically resectable tumors in some high\u2010risk LS cases.<\/jats:p>","DOI":"10.1111\/den.12707","type":"journal-article","created":{"date-parts":[[2016,8,8]],"date-time":"2016-08-08T18:27:09Z","timestamp":1470680829000},"page":"749-754","source":"Crossref","is-referenced-by-count":2,"title":["Depressed\u2010type submucosal invasive colorectal cancer in a patient with Lynch syndrome diagnosed using short\u2010interval colonoscopy"],"prefix":"10.1111","volume":"28","author":[{"given":"Kazuya","family":"Inoki","sequence":"first","affiliation":[{"name":"Endoscopy Division National Cancer Center Hospital  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Endoscopy Division National Cancer Center Hospital  Tokyo Japan"},{"name":"Genetic Medicine and Services National Cancer Center Hospital  Tokyo 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Medicine and Services National Cancer Center Hospital  Tokyo Japan"},{"name":"Cancer Screening Division, Research Center for Cancer Prevention and Screening National Cancer Center  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masau","family":"Sekiguchi","sequence":"additional","affiliation":[{"name":"Endoscopy Division National Cancer Center Hospital  Tokyo Japan"},{"name":"Cancer Screening Division, Research Center for Cancer Prevention and Screening National Cancer Center  Tokyo Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mineko","family":"Ushiama","sequence":"additional","affiliation":[{"name":"Genetic Medicine and Services National Cancer Center Hospital  Tokyo Japan"},{"name":"Group for Cancer Development and Progression, Division of Genetics National Cancer Center Research Institute  Tokyo 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