{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T06:17:40Z","timestamp":1784269060348,"version":"3.55.0"},"reference-count":13,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2017,3,15]],"date-time":"2017-03-15T00:00:00Z","timestamp":1489536000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007418","name":"Ajinomoto Pharmaceuticals","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007418","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002973","name":"Daiichi-Sankyo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002973","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008373","name":"Takeda Pharmaceutical Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008373","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004324","name":"Astellas Pharma US","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004324","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>The risk of developing colorectal cancer is higher in patients with ulcerative colitis (<jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content>) than in the general population. Guidelines recommend surveillance colonoscopy (<jats:styled-content style=\"fixed-case\">SCS<\/jats:styled-content>) to reduce mortality; however, few studies have assessed physicians\u2019 adherence to guidelines. This study was aimed to clarify the current status of <jats:styled-content style=\"fixed-case\">SCS<\/jats:styled-content> and adherence to guidelines through the characteristics of cancer\/dysplasia surveillance for <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> patients in Japan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A questionnaire was mailed to 541 physicians who attended meetings on inflammatory bowel disease.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The respondents encountered a median of 100 <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> cases. Thirty percent of the respondents had never managed a <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> patient with cancer. Fifty\u2010one percent of the respondents had never diagnosed colorectal cancer with <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content>. Forty\u2010seven percent of the respondents considered extensive colitis and left\u2010sided colitis as indications for <jats:styled-content style=\"fixed-case\">SCS<\/jats:styled-content>, and 38% carried out <jats:styled-content style=\"fixed-case\">SCS<\/jats:styled-content> regardless of the disease extent. Sixty\u2010three percent of the respondents started <jats:styled-content style=\"fixed-case\">SCS<\/jats:styled-content> at 7\u201310 years after <jats:styled-content style=\"fixed-case\">UC<\/jats:styled-content> onset, whereas 20% started <jats:styled-content style=\"fixed-case\">SCS<\/jats:styled-content> at 3 years or less. Fifty\u2010two percent of the respondents obtained targeted biopsies only, and chromoendoscopy was used by 49% of the respondents as a special technique for surveillance. Median number of biopsies at <jats:styled-content style=\"fixed-case\">SCS<\/jats:styled-content> was five per patient; it was three among patients whose biopsy was carried out by physicians who obtained targeted biopsies only and seven among those carried out by physicians who obtained step biopsies and targeted biopsies (<jats:italic>P<\/jats:italic> &lt; 0.0001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A considerable proportion of the respondents did not follow the guidelines when selecting patients for surveillance and carrying out <jats:styled-content style=\"fixed-case\">SCS<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.12803","type":"journal-article","created":{"date-parts":[[2017,1,9]],"date-time":"2017-01-09T07:16:55Z","timestamp":1483946215000},"page":"584-593","source":"Crossref","is-referenced-by-count":15,"title":["Surveillance for dysplasia in patients with ulcerative colitis: Discrepancy between guidelines and practice"],"prefix":"10.1111","volume":"29","author":[{"given":"Masaru","family":"Shinozaki","sequence":"first","affiliation":[{"name":"Department of Surgery the Institute of Medical Science the University of Tokyo Tokoyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyonori","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Research and Development Center for New Medical Frontiers School of Medicine Kitasato University Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reiko","family":"Kunisaki","sequence":"additional","affiliation":[{"name":"Inflammatory Bowel Disease Center Yokohama City University Medical Center Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadakazu","family":"Hisamatsu","sequence":"additional","affiliation":[{"name":"The Third Department of Internal Medicine Kyorin University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Naganuma","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine Keio University School of Medicine Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken\u2010ichi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Coloproctology Center Tohoku Rosai Hospital Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Iwao","sequence":"additional","affiliation":[{"name":"Center for Preventive Medicine Keio University Hospital Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuo","family":"Suzuki","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Toho University Sakura Medical Center Sakura Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamoru","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michio","family":"Itabashi","sequence":"additional","affiliation":[{"name":"Department of Surgery Institute of Gastroenterology Tokyo Women's Medical University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Torii","sequence":"additional","affiliation":[{"name":"Torii Clinic Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakazu","family":"Takazoe","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Medicine Tokyo Yamate Medical Center Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Sugita","sequence":"additional","affiliation":[{"name":"Inflammatory Bowel Disease Center Yokohama Municipal Hospital Yokohama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,15]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.48.4.526"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(83)80175-0"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.01.057"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.727"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crohns.2012.09.005"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2009.179804"},{"key":"e_1_2_8_8_1","unstructured":"Guidelines for the management of ulcerative colitis in Japan \u2013Developed through integration of evidence and consensus among experts \u2013 [cited 2016 Sep 22]. 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