{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T14:42:51Z","timestamp":1788878571586,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2017,11,22]],"date-time":"2017-11-22T00:00:00Z","timestamp":1511308800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Endoscopic ultrasonography\u2010guided hepaticogastrostomy (<jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGS<\/jats:styled-content>) is often indicated for advanced stage patients. Therefore it is important to prevent adverse events associated with <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGS<\/jats:styled-content> procedures and obtain long stent patency. <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010guided antegrade stenting (<jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content>) has been developed as an advanced technique. Thus, to prevent adverse events and achieve long stent patency, <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content> combined with <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGS<\/jats:styled-content> (<jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGAS<\/jats:styled-content>) has been reported. The aim of the present study was to evaluate the technical feasibility and efficacy of <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGAS<\/jats:styled-content> in a multicenter, prospective study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This prospective study was carried out at each hospital of the Therapeutic Endoscopic Ultrasound Group. Primary endpoint of this multicenter prospective study was stent patency of <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGAS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 49 patients were enrolled. Technical success rate of <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGS<\/jats:styled-content> was 95.9% (47\/49). <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">AS<\/jats:styled-content> failed in five patients because the guidewire could not be advanced into the intestine across the bile duct obstruction site. Therefore, <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGAS<\/jats:styled-content> was successfully carried out in 40 patients (technical success rate: 85.7%). Median overall survival was 114 days. Median stent patency including stent dysfunction and patient death was 114 days. In contrast, mean stent patency was 320 days. Adverse events were seen in 10.2% (5\/49) of cases. Hyperamylasemia was seen in four patients, and bleeding was seen in one patient.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The present study is the first to evaluate <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGAS<\/jats:styled-content>. <jats:styled-content style=\"fixed-case\">EUS<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">HGAS<\/jats:styled-content> has clinical benefit for obtaining long stent patency and avoiding adverse events, although the possibility of acute pancreatitis as a result of obstruction of the orifice of the pancreatic duct must be considered.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.12976","type":"journal-article","created":{"date-parts":[[2017,10,21]],"date-time":"2017-10-21T01:56:41Z","timestamp":1508551001000},"page":"252-259","source":"Crossref","is-referenced-by-count":77,"title":["Multicenter prospective evaluation study of endoscopic ultrasound\u2010guided hepaticogastrostomy combined with antegrade stenting (with video)"],"prefix":"10.1111","volume":"30","author":[{"given":"Takeshi","family":"Ogura","sequence":"first","affiliation":[{"name":"Therapeutic Endoscopic Ultrasound Group: TEUS Takatuki Japan"},{"name":"2nd Department of Internal Medicine Osaka Medical College Takatuki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masayuki","family":"Kitano","sequence":"additional","affiliation":[{"name":"Therapeutic Endoscopic Ultrasound Group: TEUS Takatuki Japan"},{"name":"Second Department of Internal Medicine Wakayama Medical University Wakayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamoru","family":"Takenaka","sequence":"additional","affiliation":[{"name":"Therapeutic Endoscopic Ultrasound Group: TEUS Takatuki Japan"},{"name":"Department of Gastroenterology and Hepatology Osaka\u2010Sayama 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