{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:02:15Z","timestamp":1789048935123,"version":"build-2803163510"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,1,24]],"date-time":"2018-01-24T00:00:00Z","timestamp":1516752000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Background and Aim<\/jats:title><jats:p>Endoscopic snare papillectomy (<jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>) is an effective treatment for ampullary adenoma. Argon plasma coagulation (<jats:styled-content style=\"fixed-case\">APC<\/jats:styled-content>) is widely used as an additional method to control bleeding or ablate the residual tumor. However, the efficacy of this procedure has not yet been fully evaluated. This study aimed to evaluate the usefulness of <jats:styled-content style=\"fixed-case\">APC<\/jats:styled-content> as an additional method to <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients who underwent <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content> for ampullary adenoma between September 2005 and September 2015 were retrospectively reviewed. Using propensity score matching, we compared short\u2010 and long\u2010term outcomes between the <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>\u2010with\u2010additional\u2010<jats:styled-content style=\"fixed-case\">APC<\/jats:styled-content> group (<jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">APC<\/jats:styled-content> group) and the <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>\u2010only group. Primary outcome was early post\u2010<jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content> adverse events (<jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content>), and secondary outcomes were late <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> and recurrence.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 109 patients, additional <jats:styled-content style=\"fixed-case\">APC<\/jats:styled-content> was carried out in 59 (54.1%) patients. After matching, 41 patients were included in both groups, respectively. Bleeding rate was significantly lower in the <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">APC<\/jats:styled-content> group than in the <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>\u2010only group (7.3% <jats:italic>vs<\/jats:italic> 31.7%, odds ratio\u00a0=\u00a00.180, <jats:italic>P\u00a0<\/jats:italic>&lt;<jats:italic>\u00a0<\/jats:italic>0.01). However, there were no significant differences in other procedure\u2010related early <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> such as pancreatitis (12.2% <jats:italic>vs<\/jats:italic> 19.5%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.365), cholangitis (2.4% <jats:italic>vs<\/jats:italic> 9.8%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.198), and perforation (2.4% <jats:italic>vs<\/jats:italic> 2.4%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>1.000) between the <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">APC<\/jats:styled-content> group and the <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>\u2010only group. During the follow\u2010up period (mean 904\u00a0\u00b1\u00a0868\u00a0days), papillary stricture (9.8% <jats:italic>vs<\/jats:italic> 4.9%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.405) and recurrence rates (24.4% <jats:italic>vs<\/jats:italic> 24.4%, <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.797) were not significantly different between the <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>\u00a0+\u00a0<jats:styled-content style=\"fixed-case\">APC<\/jats:styled-content> group and the <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content>\u2010only group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Additional <jats:styled-content style=\"fixed-case\">APC<\/jats:styled-content> during <jats:styled-content style=\"fixed-case\">ESP<\/jats:styled-content> may have a beneficial effect by decreasing bleeding rate without harmful effects.<\/jats:p><\/jats:sec>","DOI":"10.1111\/den.13008","type":"journal-article","created":{"date-parts":[[2017,12,30]],"date-time":"2017-12-30T02:12:44Z","timestamp":1514599964000},"page":"485-492","source":"Crossref","is-referenced-by-count":42,"title":["Usefulness of argon plasma coagulation ablation subsequent to endoscopic snare papillectomy for ampullary adenoma"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3720-9820","authenticated-orcid":false,"given":"Kwangwoo","family":"Nam","sequence":"first","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Dankook University Hospital Dankook University College of Medicine Cheonan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Jun","family":"Song","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond E.","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Medicine University of Maryland School of Medicine Baltimore USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Hui","family":"Cho","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min Keun","family":"Cho","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongwook","family":"Oh","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Do Hyun","family":"Park","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong\u2010Wan","family":"Seo","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Koo","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung\u2010Hwan","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology Department of Internal Medicine Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seunghee","family":"Baek","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Biostatistics Asan Medical Center University of Ulsan College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,1,24]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1163","article-title":"Neoplasia of the ampulla of Vater. 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