{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:28:11Z","timestamp":1790756891960,"version":"4.1.0"},"reference-count":106,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2019,2,10]],"date-time":"2019-02-10T00:00:00Z","timestamp":1549756800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Digestive Endoscopy"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>Small\u2010bowel capsule endoscopy (<jats:styled-content style=\"fixed-case\">SBCE<\/jats:styled-content>) is used widely because of its non\u2010invasive and patient\u2010friendly nature. <jats:styled-content style=\"fixed-case\">SBCE<\/jats:styled-content> can visualize entire small\u2010intestinal mucosa and facilitate detection of small\u2010intestinal abnormalities. In this review article, we focus on the current status of <jats:styled-content style=\"fixed-case\">SBCE<\/jats:styled-content>. Several platforms for <jats:styled-content style=\"fixed-case\">SBCE<\/jats:styled-content> are available worldwide. Third\u2010generation <jats:styled-content style=\"fixed-case\">SBCE<\/jats:styled-content> (PillCam<jats:sup>\u00ae<\/jats:sup> <jats:styled-content style=\"fixed-case\">SB<\/jats:styled-content>3) has a high\u2010resolution camera equipped with an adaptive frame rate system. Several software modes have been developed to reduce the reading time for capsule endoscopy and to minimize the possibility of missing lesions. The main complication of <jats:styled-content style=\"fixed-case\">SBCE<\/jats:styled-content> is capsule retention. Thus, the main contraindication for <jats:styled-content style=\"fixed-case\">SBCE<\/jats:styled-content> is known or suspected gastrointestinal obstruction unless intestinal patency is proven. Possible indications for <jats:styled-content style=\"fixed-case\">SBCE<\/jats:styled-content> are obscure gastrointestinal bleeding, Crohn's disease, small\u2010intestinal polyps and tumors, and celiac disease. Colon capsule endoscopy (<jats:styled-content style=\"fixed-case\">CCE<\/jats:styled-content>) can observe inflamed colonic mucosa non\u2010invasively, and allows for the continuous and non\u2010invasive observation of the entire intestinal tract (pan\u2010endoscopy). Recently, application of <jats:styled-content style=\"fixed-case\">CCE<\/jats:styled-content>\u00a0as pan\u2010enteric endoscopy for inflammatory bowel diseases (including Crohn's disease) has been reported. In the near future, reading for <jats:styled-content style=\"fixed-case\">CE<\/jats:styled-content> will be assisted by artificial intelligence, and reading <jats:styled-content style=\"fixed-case\">CE<\/jats:styled-content> videos for long periods will not be required.<\/jats:p>","DOI":"10.1111\/den.13346","type":"journal-article","created":{"date-parts":[[2019,1,18]],"date-time":"2019-01-18T04:28:36Z","timestamp":1547785716000},"page":"498-507","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":95,"title":["Capsule endoscopy for small\u2010intestinal disorders: Current status"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4516-5648","authenticated-orcid":false,"given":"Naoki","family":"Hosoe","sequence":"first","affiliation":[{"name":"Center for Diagnostic and Therapeutic Endoscopy School of Medicine Keio University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaoru","family":"Takabayashi","sequence":"additional","affiliation":[{"name":"Center for Diagnostic and Therapeutic Endoscopy School of Medicine Keio University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Ogata","sequence":"additional","affiliation":[{"name":"Center for Diagnostic and Therapeutic Endoscopy School of Medicine Keio University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takanori","family":"Kanai","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine Keio University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,10]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/35013140"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/den.12922"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/mge.2000.110204"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/202935"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i18.5542"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-2980.2012.00638.x"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2012.04.443"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-995783"},{"issue":"3","key":"e_1_2_11_10_1","first-page":"155","article-title":"Capsule endoscopy with PillCamSB2 versus PillCamSB3: has the improvement in technology resulted in a step forward?","volume":"110","author":"Xavier S","year":"2018","journal-title":"Rev. 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